David J. Weber

Has grant

Professor

University of Maryland

United States

Research Interests

Explore related searches

Professors in United States Professors in Cancer Biology Cancer Biology professors in United States

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

David J. Weber is a Professor at the University of Maryland, Baltimore, USA. His research primarily focuses on drug design, protein interactions, and cancer biology, with recent publications exploring topics such as multiconformation virtual screening, ligand dissociation kinetics, and the functional roles of various proteins in disease processes. Additionally, he investigates the structural insights related to toxins and receptors that influence cancer phenotypes and pathogenic responses.

Recent Grants

Grant: Close

Structure-based targeting of the C. difficile toxin (CDT) from hypervirulent bacterial strains

Open Date: 2021-08-06

Close Date: 2022-07-30

Grant: Close

Signal Propagation in Protein Allostery: Mechanism and Evolution

Open Date: 2019-04-01

Close Date: 2022-12-31

Grant: Close

Rational targeting of protein translation of cancer treatments

Open Date: 2013-07-01

Close Date: 2019-06-30

Grant: Close

Multimode Fluorescence Microplate Reader

Open Date: 2011-04-01

Close Date: 2012-03-31

Grant: Close

950 MHz NMR Spectrometer with Cryogenic Probe

Open Date: 2010-05-27

Close Date: 2012-05-26

Articles (17)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Collaborators (11)

Yuji Zhang

Professor

University of Maryland

UNITED STATES

View details

Alex MacKerell

Grollman Glick Professor

University of Maryland School of Pharmacy

UNITED STATES

View details

Xi Chen

National Cancer Institute

UNITED STATES

View details

Wenbo Yu

University of Maryland

UNITED STATES

View details

Riya Samanta

University of Maryland at College Park

UNITED STATES

View details

Maureen A. Kane

UNITED STATES

View details

Mary Cook

University of Maryland School of Medicine

UNITED STATES

View details

Vincent Njar

Professor

University of Maryland

UNITED STATES

View details

Erick O. Hernández‐Ochoa

UNITED STATES

View details

Roy A. Mariuzza

UNITED STATES

View details

Ashley N. Brown

UNITED STATES

View details

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts before you send them.

David J. Weber

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (17)

Bile Acids Are Potential Negative Allosteric Modulators of M1 Muscarinic Receptors

High-Throughput Ligand Dissociation Kinetics Predictions Using Site Identification by Ligand Competitive Saturation

Hierarchical AF2RAVE for Multiconformation Virtual Screening Targeting S100 Ca2+-Binding Proteins

High Throughput Ligand Dissociation Kinetics Predictions using Site-Identification by Ligand Competitive Saturation

High Throughput Ligand Dissociation Kinetics Predictions using Site-Identification by Ligand Competitive Saturation

Unveiling the intricate role of S100A1 in regulating RyR1 activity: A commentary on “Structural insights into the regulation of RyR1 by S100A1”

Structural and Functional Insights into the Delivery Systems of Bacillus and Clostridial Binary Toxins

Transglutaminase 2 Binds to the CD44v6 Cytoplasmic Domain to Stimulate CD44v6/ERK1/2 Signaling and Maintain an Aggressive Cancer Phenotype

Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal Degradation

Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum α-Glucosidase I with Anti-SARS-CoV-2 Activity.

Computer-Aided Drug Design: An Update.

<sup>1</sup>H, <sup>13</sup>C, and <sup>15</sup>N assignments of the mRNA binding protein hnRNP A18.

Binding and Functional Folding (BFF): A Physiological Framework for Studying Biomolecular Interactions and Allostery.

Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models

Transcriptome profiling reveals that VNPP433-3β, the lead next-generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial-mesenchymal transition and stem cell markers.

Nano-Assembly of Quisinostat and Biodegradable Macromolecular Carrier Results in Supramolecular Complexes with Slow-Release Capabilities

1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1β/I2PP2A oncoprotein (residues 23–225)

Collaborators (11)

Yuji Zhang

Alex MacKerell

Xi Chen

Wenbo Yu

Riya Samanta

Maureen A. Kane

Mary Cook

Vincent Njar

Erick O. Hernández‐Ochoa

Roy A. Mariuzza

Ashley N. Brown

Make your next move.