David Kaczka

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Gilbert E. Kinyon Professor

Iowa State University

United States

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About

David Kaczka is the Gilbert E. Kinyon Professor at the University of Iowa, USA. His research focuses on respiratory mechanics, airway gas flow dynamics, and the use of computational modeling in evaluating lung function. Recent publications include studies on ventilation heterogeneity in asthmatics and the development of advanced ventilatory technologies.

Recent Grants

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Preclinical Evaluation of Multifrequency Oscillatory Ventilation in a Large-Animal Model of Acute Respiratory Failure

Open Date: 2020-01-01

Close Date:

Grant: Close

Device for Multi-Frequency Oscillatory Ventilation in Adult Patients with the Acute Respiratory Distress Syndrome

Open Date: 2018-09-20

Close Date: 2019-08-31

Grant: Close

Optimizing Ventilation Distribution and Gas Exchange in Combat-Related Lung Injury Using Multifrequency Oscillation

Open Date: 2014-10-01

Close Date: 2015-09-01

Grant: Close

Optimizing Mechanical Ventilation in Acute Lung Injury

Open Date: 2008-04-01

Close Date: 2012-08-31

Grant: Close

Optimizing Mechanical Ventilation in Acute Lung Injury

Open Date: 2008-04-01

Close Date: 2012-08-31

Articles (26)

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2021

Collaborators (7)

Tilo Winkler

Associate Professor of Anaesthesia, Ph.D.

Massachusetts General Hospital and Harvard Medical School

UNITED STATES

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Alejandro Comellas

Professor

Iowa State University

UNITED STATES

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Michaela Kollisch-Singule

Associate Professor

Arkansas Children's Hospital

UNITED STATES

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Merryn Tawhai

Professor

University of Auckland

NEW ZEALAND

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Jacob Herrmann

Assistant Professor

The University of Iowa

UNITED STATES

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Wei Shao

Assistant Professor

University of Florida

UNITED STATES

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James Pankow

University of Minnesota

UNITED STATES

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David Kaczka

Research Interests

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About

Recent Grants

Articles (26)

Simulation of central airway gas flow dynamics during conventional and multi-frequency ventilation

Finite element simulation of lung parenchyma deformation based on porcine data

Virtual patient model for evaluating automated inspired oxygen control

Upper airway CO2 clearance during noninvasive ventilation: a perspective on mask design using computational fluid dynamics

Assessment of ventilation heterogeneity and particle deposition in asthmatics using combined SPECT/CT imaging and computational modeling approaches

Structural and functional characteristics of healthy and injured porcine lungs during deflation: a quantitative CT imaging analysis

Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study

Design and implementation of a computer-controlled hybrid oscillatory ventilator

Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model

Imaging the lung in ARDS: a primer

Mechanical power and ventilator-induced lung injury: what does physics have to say?

Time-Controlled Adaptive Ventilation (TCAV): a personalized strategy for lung protection

Forward computational modeling of respiratory airflow

Effects of lung injury and abdominal insufflation on respiratory mechanics and lung volume during time-controlled adaptive ventilation

First stabilize and then gradually recruit: a paradigm shift in protective mechanical ventilation for acute lung injury

Ratchet recruitment in the Acute Respiratory Distress Syndrome: lessons from the newborn cry

Sustained vs. intratidal recruitment in the injured lung during airway pressure release ventilation: a computational modeling perspective

Positron emission tomography-computed tomography imaging of selective lobar delivery of stem cells in ex vivo lung model of mechanical ventilation

Assessment of heterogeneity in lung structure and function during mechanical ventilation: a review of methodologies

A comparison of endotracheal tube compensation techniques for the measurement of respiratory mechanical impedance at low frequencies

Pulmonary blood volume among older adults in the community: the MESA Lung Study

Unshrinking the baby lung to calm the VILI vortex

Clinical significance and applications of oscillometry

Regional gas transport during conventional and oscillatory ventilation assessed by Xenon-enhanced computed tomography

Effects of lung injury on regional aeration and expiratory time constants: insights from four-dimensional computed tomography image registration

Case studies in physiology: temporal variations of the lung parenchyma and vasculature in asymptomatic COVID-19 pneumonia: a multi-spectral CT assessment

Collaborators (7)

Tilo Winkler

Alejandro Comellas

Michaela Kollisch-Singule

Merryn Tawhai

Jacob Herrmann

Wei Shao

James Pankow

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