David Landreth Van Vactor, Jr.

Professor

Harvard Medical School

United States

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David Landreth Van Vactor, Jr. is a Professor at Harvard Medical School in the United States. His research focuses on neurobiology, particularly in the context of Huntington's disease, synapse development, and the role of microRNA in synaptic function. He employs innovative techniques such as single-nuclei transcriptome analysis and 3D particle tracking to explore cellular mechanisms affecting neuromuscular junctions and glial cells.

Articles (8)

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2022

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2022

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2021

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2021

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2020

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2020

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Associate Professor of Genome Biology

University of Oxford

UNITED KINGDOM

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David Landreth Van Vactor, Jr.

Research Interests

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Articles (8)

An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells.

Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits.

Control of feeding by Piezo-mediated gut mechanosensation in Drosophila

miRNA: local guardians of presynaptic function in plasticity and disease.

Synapse development and maturation at the drosophila neuromuscular junction.

3D Particle Tracking for Noninvasive In Vivo Analysis of Synaptic Microtubule Dynamics in Dendrites and Neuromuscular Junctions of Drosophila.

Drosophila enabled promotes synapse morphogenesis and regulates active zone form and function.

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells.

Collaborators (6)

James Korkola

Nilay Yapici

Katherine Thompson-Peer

Elizabeth McNeill

Yangkyun Oh

Tudor Fulga

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