David Landsman

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Acting Branch Chief

United States

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David Landsman is the Acting Branch Chief at the National Institutes of Health/National Library of Medicine in the United States. His research areas include cancer genomics, protein binding dynamics, and the role of transcription factors in cell type specificity and chromatin structure. Recent publications focus on histone mutations and their impact on DNA repair, as well as advancements in transcriptome assembly and enhancer biology.

Recent Grants

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Gene Regulatory Sequences And Protein Binding in Genome Sequences

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Structural And Functional Analysis Of Protein Sequence Families

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Articles (12)

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2025

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2025

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2024

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2024

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2024

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2023

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (3)

Vladimir Teif

Senior Lecturer

University of Essex

UNITED KINGDOM

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Alexey Onufriev

professor

Virginia Tech

UNITED STATES

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Michael Galperin

UNITED STATES

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David Landsman

Research Interests

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Recent Grants

Articles (12)

Cancer histone mutations impact protein binding and DNA repair with possible links to genomic instability

COG database update 2024

Detection of new pioneer transcription factors as cell-type-specific nucleosome binders

Detection of new pioneer transcription factors as cell-type-specific nucleosome binders

GTax: improving de novo transcriptome assembly by removing foreign RNA contamination

Clustered and diverse transcription factor binding underlies cell type specificity of enhancers for housekeeping genes.

DNA methylation cues in nucleosome geometry, stability and unwrapping

Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails

A model of active transcription hubs that unifies the roles of active promoters and enhancers

Histone tails as signaling antennas of chromatin

Transcriptome annotation in the cloud: complexity, best practices, and cost

COG database update: focus on microbial diversity, model organisms, and widespread pathogens

Collaborators (3)

Vladimir Teif

Alexey Onufriev

Michael Galperin

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