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David M Sabatini

Sr. Group Leader

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

Czech Republic

Research Interests

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Professors in Biochemistry

Articles (6)

Year:

2026

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Collaborators (7)

Martin Taylor

Assistant Professor

Brown University

UNITED STATES

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Timothy O'Meara

Harvard University

UNITED STATES

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Jonathan Weissman

Whitehead Institute for Biomedical Research

UNITED STATES

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Patrick Jouandin

FRANCE

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Nam Chu

Assistant Professor

Ohio State University

UNITED STATES

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Yi Shi

Professor (tenure) and Director, Center for Protein Engineering and Therapeutics

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Kacper Rogala

Assistant Professor

Stanford University

UNITED STATES

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David M Sabatini

Research Interests

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Articles (6)

Atlas of Lysosomal Aging Reveals a Metabolite Signature Shared with Lysosomal Storage Disorders

Structural Basis for the Recruitment and Selective Phosphorylation of Akt by mTORC2

Structural basis for the dynamic regulation of mTORC1 by amino acids

Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Rag–Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway

Collaborators (7)

Martin Taylor

Timothy O'Meara

Jonathan Weissman

Patrick Jouandin

Nam Chu

Yi Shi

Kacper Rogala

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