david o'connor

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University of Wisconsin-Madison

United States

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About

David O'Connor is a Professor at the University of Wisconsin Madison in the United States. His research focuses on areas including computed tomography radiomics, machine learning applications in medical predictions, and the genomic characteristics of non-human primate models. He has contributed significantly to understanding viral infections, including SARS-CoV-2, and the implications of HLA testing in cynomolgus macaques.

Recent Grants

Grant: Close

GBV-C-mediated protection from AIDS in humans and GBV-C/SIV co-infected macaques

Open Date: 2015-08-07

Close Date: 2019-07-31

Grant: Close

Identifying Common T Cell Responses to Major Pathogens in Rhesus Macaques

Open Date: 2014-09-01

Close Date: 2018-05-31

Grant: Close

NHP MHC Gene Discovery and Typing Technology Development

Open Date: 2011-04-01

Close Date: 2016-03-31

Grant: Close

Defining the importance of CD8+ T Cell Breadth in SIV/HIV protective immunity

Open Date: 2009-09-15

Close Date: 2015-08-31

Grant: Close

Exploring in vitro and in vivo T cell immunity to SIV with MHC-identical macaques

Open Date: 2009-04-01

Close Date: 2015-06-30

Articles (19)

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2025

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2021

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2020

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2020

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2020

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2020

Collaborators (4)

C. Paul Morris

National Institute of Allergy and Infectious Diseases

UNITED STATES

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Natasha Clark

University of Wisconsin-Madison

UNITED STATES

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Ronald Harris

Baylor College of Medicine

UNITED STATES

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Matthew Aliota

University of Minnesota

UNITED STATES

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david o'connor

Research Interests

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Contact this professor

About

Recent Grants

Articles (19)

Computed Tomography Radiomics and Machine Learning for Prediction of Histology-Based Hepatic Steatosis Scores

Complete Genomic Assembly of Mauritian Cynomolgus Macaque Killer Ig-like Receptor and Natural Killer Group 2 Haplotypes

Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge

A severe acute respiratory coronavirus virus 2 (SARS-CoV-2) nosocomial cluster with inter-facility spread: Lessons learned

Adaptation of HLA testing to characterize the cynomolgus macaque MHC polymorphisms and alloantibody signatures

Author Correction: Metagenomic sequencing detects human respiratory and enteric viruses in air samples collected from congregate settings (Scientific Reports, (2023), 13, 1, (21398), 10.1038/s41598-023-48352-6)

Persistent SARS-CoV-2 infection: significance and implications

Complete sequencing of a cynomolgus macaque major histocompatibility complex haplotype

A new genotype of hepatitis A virus causing transient liver enzyme elevations in Mauritius-origin laboratory-housed Macaca fascicularis

Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants

Neonatal Development in Prenatally Zika Virus-Exposed Infant Macaques with Dengue Immunity

Consistent ultra-long DNA sequencing with automated slow pipetting

Acute SARS-CoV-2 infections harbor limited within-host diversity and transmit via tight transmission bottlenecks

Oil immersed lossless total analysis system for integrated RNA extraction and detection of SARS-CoV-2

Development and Characterization of a cDNA-Launch Recombinant Simian Hemorrhagic Fever Virus Expressing Enhanced Green Fluorescent Protein: ORF 2b’ Is Not Required for In Vitro Virus Replication

Functional Interactions of Common Allotypes of Rhesus Macaque FcγR2A and FcγR3A with Human and Macaque IgG Subclasses

Discovery of Lanama Virus, a Distinct Member of Species <i>Kunsagivirus C</i> (<i>Picornavirales</i>: <i>Picornaviridae</i>), in Wild Vervet Monkeys (<i>Chlorocebus pygerythrus</i>)

Discovery of a Novel Simian Pegivirus in Common Marmosets (<i>Callithrix jacchus</i>) with Lymphocytic Enterocolitis

Characterization of 100 extended major histocompatibility complex haplotypes in Indonesian cynomolgus macaques

Collaborators (4)

C. Paul Morris

Natasha Clark

Ronald Harris

Matthew Aliota

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