David Rawlings

Professor

University of Washington

United States

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David Rawlings is a Professor at the University of Washington, USA. His research focuses on regulatory T cell functions, immune dysregulation, and the application of gene editing technologies such as CRISPR/Cas9. Recent publications include studies on HLA-A2 CAR engineering, PI3Kδ signaling impacts, and molecular signatures related to antibody secretion in human plasma cells.

Articles (10)

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

Collaborators (2)

richard james

Associate Professor

University of Washington

UNITED STATES

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Shaun W. Jackson

UNITED STATES

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David Rawlings

Research Interests

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Articles (10)

HLA-A2 CAR/IL-2-CISC engineered Treg display robust in vitro and in vivo antigen-specific regulatory function

Activated PI3Kδ Specifically Perturbs Mouse Regulatory T Cell Homeostasis and Function Leading to Immune Dysregulation

Dual-locus, dual-HDR editing permits efficient generation of antigen-specific regulatory T cells with robust suppressive activity

SEC-seq: association of molecular signatures with antibody secretion in thousands of single human plasma cells

PTPN22 R620W gene editing in T cells enhances low-avidity TCR responses

Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction

CRISPR/Cas9-Mediated Insertion of HIV Long Terminal Repeat within BACH2 Promotes Expansion of T Regulatory–like Cells

Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing ER stress

TACI haploinsufficiency protects against BAFF‐driven humoral autoimmunity in mice

T cells selectively filter oscillatory signals on the minutes timescale

Collaborators (2)

richard james

Shaun W. Jackson

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