David Weiss

Professor

The University of Iowa

United States

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David Weiss is a Professor at The University of Iowa, USA. His research focuses on bacterial cell wall synthesis, particularly in Clostridioides difficile and Escherichia coli, as evidenced by his recent publications on peptidoglycan synthesis and essential genes. His work also explores the interactions between various bacterial components and their implications for cell viability and antibiotic resistance.

Articles (12)

Year:

2025

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2025

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2025

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2025

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2024

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2024

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2024

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2022

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2022

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2022

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Iowa State University

UNITED STATES

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David Weiss

Research Interests

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Articles (12)

FtsZ-mediated spatial–temporal control over septal cell wall synthesis

Analysis of Essential Genes in Clostridioides difficile by CRISPRi and Tn-seq.

Third track model for coordination of septal peptidoglycan synthesis and degradation by FtsN in Escherichia coli

Identification of two glycosyltransferases required for synthesis of membrane glycolipids in Clostridioides difficile

Identification of a family of peptidoglycan transpeptidases reveals that Clostridioides difficile requires noncanonical cross-links for viability

Identification of Clostridioides difficile mutants with increased daptomycin resistance

The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells

FtsN maintains active septal cell wall synthesis by forming a processive complex with the septum-specific peptidoglycan synthases in E. coli.

Comparative Study of Bacterial SPOR Domains Identifies Functionally Important Differences in Glycan Binding Affinity

The WalRK Two-Component System Is Essential for Proper Cell Envelope Biogenesis in Clostridioides difficile

DrpB (YedR) Is a Nonessential Cell Division Protein in Escherichia coli.

Nitric oxide disrupts bacterial cytokinesis by poisoning purine metabolism

Collaborators (6)

David Popham

Richard Helm

Jon Houtman

Ryan Bezy

Jian Liu

Craig Ellermeier

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