Davit A Potoyan

Iowa State University

United States

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Articles (19)

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

The liquid–liquid phase separation of protein and nucleic acid mixtures drives the formation of numerous membraneless compartments in cells.

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (4)

Ibraheem Alshareedah

Teaching Assistant /Research

University at Buffalo

UNITED STATES

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Julien Roche

Assistant Professor

Iowa State University

UNITED STATES

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Priya R Banerjee

Associate Professor

University at Buffalo

UNITED STATES

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Holger Wille

CANADA

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Davit A Potoyan

Research Interests

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Articles (19)

Determinants of viscoelasticity and flow activation energy in biomolecular condensates

Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions

Protein thermal sensing regulates physiological amyloid aggregation

Illuminating Protein Allostery by Chemically Accurate Contact Response Analysis (ChACRA)

Atomistic insights into the reentrant phase-transitions in polyuracil and polylysine mixtures

An α-ketoglutarate conformational switch controls iron accessibility, activation, and substrate selection of the human FTO protein

Molecular Drivers of Aging in Biomolecular Condensates: Desolvation, Rigidification, and Sticker Lifetimes

Energy landscapes of homopolymeric RNAs revealed by deep unsupervised learning

Four-Dimensional Mesoscale Liquid Model of Nucleus Resolves Chromatin's Radial Organization

Re-entrant transitions of locally stiff RNA chains in the presence of polycations leads to gelated architectures

Re-entrant transitions of locally stiff RNA chains in the presence of polycations leads to gelated architectures

Temperature sensitive contact modes allosterically gate TRPV3

Temperature-sensitive contacts in disordered loops tune enzyme I activity

RNA chain length and stoichiometry govern surface tension and stability of protein-RNA condensates

Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides

The interplay of chromatin phase separation and lamina interactions in nuclear organization

Liquid–liquid phase separation driven compartmentalization of reactive nucleoplasm

Phase transition of RNA−protein complexes into ordered hollow condensates

Hybrid Thermophilic/Mesophilic Enzymes Reveal a Role for Conformational Disorder in Regulation of Bacterial Enzyme I

Collaborators (4)

Ibraheem Alshareedah

Julien Roche

Priya R Banerjee

Holger Wille

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