Deepak Deshpande

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Associate Professor

Thomas Jefferson University

United States

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About

Dr. Deepak Deshpande is an Associate Professor at Thomas Jefferson University in the United States. His research focuses on airway smooth muscle physiology and its implications in obstructive airway diseases and asthma. Recent publications explore topics including tRNA-derived RNAs in immune cell differentiation, calcium signaling in smooth muscle, and innovative therapeutic strategies for respiratory disorders.

Recent Grants

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Diacylglycerol kinase in airway smooth muscle functions

Open Date: 2019-04-01

Close Date: 2023-02-28

Grant: Close

Biased agonism and conformational heterogeneity of beta adrenergic receptors in bronchodilation

Open Date: 2017-12-20

Close Date: 2019-11-30

Grant: Close

Functional Diversity of Compartmentalized Calcium Signaling in Airway Smooth Muscle

Open Date: 2017-12-15

Close Date: 2021-11-30

Grant: Close

Evaluation of novel substrate specific inhibitors of ERK1/2 in the treatment of asthma

Open Date: 2016-06-10

Close Date: 2019-05-31

Grant: Close

Molecular basis of age-dependent changes in airway smooth muscle functions

Open Date: 2012-08-01

Close Date: 2018-05-31

Articles (16)

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2025

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2022

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2021

Collaborators (3)

Pawan Sharma

Thomas Jefferson University

UNITED STATES

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Dale Tang

Assistant/Associate/Full Professor

Albany Medical College

UNITED STATES

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Silas Leavesley

Professor

University of South Alabama

UNITED STATES

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Deepak Deshpande

Research Interests

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About

Recent Grants

Articles (16)

Profile of tRNA-derived short non-coding RNAs during monocyte differentiation and their role in macrophage survival

Biased Orthosteric Agonism and Allosteric Modulation: Emerging Strategies for Developing New Class of β-Agonists for Obstructive Airway Diseases

Spatiotemporal calcium signaling patterns underlying opposing effects of histamine and TAS2R agonists in airway smooth muscle

A-Kinase-Anchoring-Protein Subtypes Differentially Regulate GPCR Signaling and Function in Human Airway Smooth Muscle

CD38/cADPR‐mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1

Molecular mechanism of bitter taste receptor agonist‐mediated relaxation of airway smooth muscle

Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma

Proteomics-Based Approach for Detailing the Allergenic Profile of Cannabis Chemotypes

Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation

Comparing Performance of Spectral Image Analysis Approaches for Detection of Cellular Signals in Time-Lapse Hyperspectral Imaging Fluorescence Excitation-Scanning Microscopy

Interleukin 31 receptor α promotes smooth muscle cell contraction and airway hyperresponsiveness in asthma

Reactive Oxygen Species Behaving Badly: Oxidized Phosphatidylcholines Corrupt Ca2+ Signaling in Airway Smooth Muscle

In silico identification of a β 2 -adrenoceptor allosteric site that selectively augments canonical β 2 AR-Gs signaling and function

Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma

Autocrine regulation of airway smooth muscle contraction by diacylglycerol kinase

Dysregulated retinoic acid signaling in airway smooth muscle cells in asthma

Collaborators (3)

Pawan Sharma

Dale Tang

Silas Leavesley

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