Demetrios Vavvas

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Harvard Medical School

United States

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About

Demetrios Vavvas is a Professor at Harvard Medical School in the United States. His research focuses on ophthalmology, particularly exploring age-related macular degeneration, diabetic retinopathy, and inherited retinal diseases. Recent articles highlight his contributions to understanding the relationship between systemic conditions and ocular manifestations, as well as advancements in therapeutic interventions for visual restoration.

Recent Grants

Grant: Close

Necroptosis, neuroprotection and axonal regeneration in retina ganglion cell injury

Open Date: 2015-04-01

Close Date: 2019-03-31

Grant: Close

Necroptosis and Neuroprotection in AMD

Open Date: 2013-03-01

Close Date: 2015-02-28

Articles (20)

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2020

Collaborators (7)

Eleftherios Paschalis Ilios

Associate Professor

Harvard Medical School

UNITED STATES

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Deeba Husain

Professor

Harvard Medical School

UNITED STATES

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Joan Miller

Ophthalmologist-in-Chief

Brigham and Women's Hospital

UNITED STATES

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Rufino Silva

Aggregate Professor of Ophthalmology

University of Coimbra

PORTUGAL

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Kinga Bujakowska

Assistant Professor

Harvard University

UNITED STATES

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James Chodosh

Professor and Chair

University of New Mexico

UNITED STATES

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Naiwen Cui

Broad Institute

UNITED STATES

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Demetrios Vavvas

Research Interests

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Recent Grants

Articles (20)

Ophthalmological manifestations in a cohort of Cowden syndrome patients in a large tertiary healthcare system

Inner Plexiform Layer Substrata Are Discernible with Commercial OCT and Affected by Aging

Systematic Review of Proteomics in Age-Related Macular Degeneration and Pathway Analysis of Significant Protein Changes

Plasma and Urine Metabolites Associated with Microperimetric Retinal Sensitivity in Age-Related Macular Degeneration

Metabolomic-derived endotypes of age-related macular degeneration (AMD): a step towards identification of disease subgroups

Visual restoration with KPro after face allotransplantation with a grade III phthisical eye

Structure-based network analysis predicts pathogenic variants in human proteins associated with inherited retinal disease

Differences in effects of some newer-generation anti-diabetics on diabetic retinopathy versus nephropathy

Effects of newer-generation anti-diabetics on diabetic retinopathy: a critical review

Opposing Roles of Blood-Borne Monocytes and Tissue-Resident Macrophages in Limbal Stem Cell Damage after Ocular Injury

Sustained Inhibition of VEGF and TNF-α Achieves Multi-Ocular Protection and Prevents Formation of Blood Vessels after Severe Ocular Trauma

Systemic dyslipidemia in age-related macular degeneration: an updated systematic review and meta-analysis

RIPK necrotic cell death pathway in both donor photoreceptor and host immune cells synergize to affect photoreceptor graft survival

Peripheral monocytes and neutrophils promote photoreceptor cell death in an experimental retinal detachment model

UVA induces retinal photoreceptor cell death via receptor interacting protein 3 kinase mediated necroptosis

Dyslipidemia in age-related macular degeneration

Receptor interacting protein 3 kinase, not 1 kinase, through MLKL-mediated necroptosis is involved in UVA-induced corneal endothelium cell death

Reply to Green and Hume: Nonmicroglia peripheral immune effects of short-term CSF1R inhibition with PLX5622

Concerns about the interpretation of OCT and fundus findings in COVID-19 patients in recent Lancet publication

CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages

Collaborators (7)

Eleftherios Paschalis Ilios

Deeba Husain

Joan Miller

Rufino Silva

Kinga Bujakowska

James Chodosh

Naiwen Cui

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