denis duboule

Professor

Collège de France

France

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Professor Denis Duboule is a faculty member at Collège de France, France. His research focuses on developmental biology, particularly in the areas of gene expression, embryonic patterning, and the genetic underpinnings of congenital disorders. His recent publications explore CTCF-dependent mechanisms, limb development, and enhancers within regulatory landscapes in both murine and avian models.

Articles (13)

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2025

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

Collaborators (5)

Joost Woltering

Assistant professor

University of Konstanz

GERMANY

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PIERRE OSTEIL

Assistant professor

Université Clermont Auvergne

FRANCE

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Leonardo Beccari

SWITZERLAND

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Guillaume Andrey

Assistant Professor

University of Geneva

SWITZERLAND

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Marian Ros

Profesor de Investigación

Consejo Superior de Investigaciones Cientificas

SPAIN

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denis duboule

Research Interests

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Articles (13)

Fine-tuning mechanical constraints reveals uncoupled patterning and gene expression programs in murine gastruloids

CTCF-dependent insulation of Hoxb13 and the heterochronic control of tail length

A CTCF-dependent mechanism underlies the Hox timer: relation to a segmented body plan

Genetic cold cases: lessons from solving complex congenital limb disorders

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos

Time‐sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis

Context-dependent enhancer function revealed by targeted inter-TAD relocation

Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken

Hox13-Mediated Dbx2 Regulation In Limbs Suggests Inter-Tad Sharing Of Enhancers.

Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

Induction of a chromatin boundary in vivo upon insertion of a TAD border

Chromatin topology and the timing of enhancer function at the HoxD locus

Collaborators (5)

Joost Woltering

PIERRE OSTEIL

Leonardo Beccari

Guillaume Andrey

Marian Ros

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