DENIS MIGLIORINI

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Assistant Professor

University of Geneva

Switzerland

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Recent Grants

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Brain tumor and immune cell engineering Laboratory

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Rational design of inhibitory chimeric antigen receptor (iCAR) to prevent anti CD19 CAR-T cell related neurotoxicity in B-cell malignancies

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Exploiting addiction to C-KIT pathway as a therapeutic strategy for Glioblastoma

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Identification of novel CAR T-cell targets for cancer immunotherapy

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Towards automated manufacturing of clinical grade CAR T-cells for cancer treatment

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Articles (18)

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (9)

Jolanta Kunikowska

Medical University of Warsaw

POLAND

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Olivier Jordan

University of Geneva

SWITZERLAND

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Mathias Wenes

Assistant Professor

University of Geneva

SWITZERLAND

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Ping-Chih Ho

University of Lausanne

SWITZERLAND

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Michele De Palma

Associate Professor

École Polytechnique Fédérale de Lausanne

SWITZERLAND

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Caroline Arber

Research Group Leader, Attending Physician, Associate Professor

Lausanne University Hospital

SWITZERLAND

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Giusy Di Conza

University of Lausanne

SWITZERLAND

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STEVEN BREM

Professor

Hospital of the University of Pennsylvania

UNITED STATES

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Mikael J. Pittet

University of Geneva

SWITZERLAND

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DENIS MIGLIORINI

Research Interests

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Recent Grants

Articles (18)

Hypoxic glioblastoma-cell-derived extracellular vesicles impair cGAS-STING activity in macrophages

Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Reductive carboxylation epigenetically instructs T cell differentiation

Identification of a miRNA multi-targeting therapeutic strategy in glioblastoma

Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma

The potential role of the microbiota in prostate cancer pathogenesis and treatment

IOA-244 is a Non–ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance

CAR T-Based Therapies in Lymphoma: A Review of Current Practice and Perspectives

Diagnostic Accuracy of PET/CT or PET/MRI Using PSMA-Targeting Radiopharmaceuticals in High-Grade Gliomas: A Systematic Review and a Bivariate Meta-Analysis

Cancer vaccines

Clinical relevance of tumour-associated macrophages

The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function

From Focused Ultrasound Tumor Ablation to Brain Blood Barrier Opening for High Grade Glioma: A Systematic Review

Choosing the Right Tool for Genetic Engineering: Clinical Lessons from Chimeric Antigen Receptor-T Cells

Clonal Evolution of a High-Grade Pediatric Glioma With Distant Metastatic Spread

Challenging Hurdles of Current Targeting in Glioblastoma: A Focus on Immunotherapeutic Strategies.

Allogeneic CAR T Cells: An Alternative to Overcome Challenges of CAR T Cell Therapy in Glioblastoma.

Collaborators (9)

Jolanta Kunikowska

Olivier Jordan

Mathias Wenes

Ping-Chih Ho

Michele De Palma

Caroline Arber

Giusy Di Conza

STEVEN BREM

Mikael J. Pittet

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