Derek P Claxton

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Assistant Professor

Vanderbilt University

United States

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Recent Grants

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STRUCTURE AND DYNAMICS OF A HOMOLOGUE OF NEUROTRANSMITTER SODIUM SYMPORTERS

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STRUCTURAL INVESTIGATION OF A GABA RECEPTOR SUBTYPE

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Articles (8)

Year:

2024

Year:

2023

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2022

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2022

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2021

Year:

2021

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2020

Year:

2020

Collaborators (3)

Karin Bosma

Vanderbilt University Medical Center

UNITED STATES

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Lea Davis

Assistant Professor

Vanderbilt University

UNITED STATES

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Melanie Ohi

Professor

University of Michigan

UNITED STATES

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Derek P Claxton

Research Interests

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Recent Grants

Articles (8)

Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model

Simulations reveal the role of glucose-6-phosphatase mutations in glycogen storage disease

Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose

Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1

Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na+ in ion-coupled drug efflux

Principles of Alternating Access in Multidrug and Toxin Extrusion (MATE) Transporters

Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy

Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter

Collaborators (3)

Karin Bosma

Lea Davis

Melanie Ohi

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