Despoina Mavridou

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Assistant Professor

University of Texas at Austin

United States

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About

Despoina Mavridou is an Assistant Professor at the University of Texas at Austin, USA. Her research focuses on antibiotic resistance, specifically in Gram-negative bacteria, and includes studying the antimicrobial activity of nanobodies and peptide macrocycles. Recent publications highlight her work on colistin resistance mechanisms and the role of protein folding in antibiotic efficacy.

Recent Grants

Grant: Open

The interplay between cell envelope protein homeostasis and antibiotic resistance in Gram-negative bacteria

Open Date: 2021-11-01

Close Date: 2026-10-31

Grant: Close

Disulfide bond formation in Pseudomonas species

Open Date: 2017-09-29

Close Date: 2020-09-29

Grant: Close

Characterisation of disulfide bond formation in bacterial pathogens: Unravelling the adaptation of a classical pathway into a virulence aid.

Open Date: 2015-11-01

Close Date: 2020-10-31

Articles (11)

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2025

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

Year:

2021

Year:

2021

Collaborators (16)

Kavita Gadar

University of Birmingham

UNITED KINGDOM

Despoina Mavridou

Research Interests

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About

Recent Grants

Articles (11)

Resurfacing promotes antibacterial activity of a lipid A–binding nanobody

Disrupting iron homeostasis can potentiate colistin activity and overcome colistin resistance mechanisms in Gram-Negative Bacteria

Carbapenem-Resistant and ESBL-Producing Enterobacterales Emerging in Central Texas

Designing and identifying β-hairpin peptide macrocycles with antibiotic potential

The biogenesis of β-lactamase enzymes

Blocking protein folding to fight antibiotic resistance

Breaking antimicrobial resistance by disrupting extracytoplasmic protein folding

Droplet printing reveals the importance of micron-scale structure for bacterial ecology

Colistin resistance in Escherichia coli confers protection of the cytoplasmic but not outer membrane from the polymyxin antibiotic

Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells

Harnessing the potential of bacterial oxidative folding to aid protein production

Collaborators (16)

Kavita Gadar

Hannah Pugh

Ravinash Krishna Kumar

David Albesa-Jové

Jennifer Parker

Kevin Foster

Wook Kim

Ronan R. McCarthy

William Smith

Laura Nolan

Gerald Larrouy-Maumus

Patricia Bernal

Bryan Davies

Andrew M. Edwards

Claus O Wilke

Diego Gonzalez

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