Dierk Niessing

Professor & Head of Institute

Ulm University

Germany

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Professor Dierk Niessing is the Head of Institute at Ulm University, Germany. His research focuses on RNA biology, neurodevelopmental disorders, and protein analysis, as evidenced by his recent publications on tRNA methyltransferases and PURA syndrome. He explores the structural dynamics of RNA-binding proteins and their role in gene regulation and disease mechanisms.

Articles (13)

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2020

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2020

Collaborators (10)

Oliver Binas

Goethe University Frankfurt

GERMANY

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Tim Gruene

Senior Scientist / Head of Centre

Universität Wien

AUSTRIA

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Erwin Märtlbauer

Ludwig-Maximilians-Universität München

GERMANY

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Ejona Rusha

Head of Core Facility

Helmholtz Zentrum München

GERMANY

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Michael Hildebrand

A/Professor

University of Melbourne

AUSTRALIA

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Ilaria Testa

Assistant Professor, SciLife fellow

SWEDEN

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Himanshu Goel

University of Newcastle Australia

AUSTRALIA

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Andriy Chmyrov

Deputy Head, Research Group Leader

German Cancer Research Center (DKFZ)

GERMANY

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Ingrid Scheffer

University of Melbourne

AUSTRALIA

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Kathi Zarnack

Full Professor

Julius-Maximilians-Universität Würzburg

GERMANY

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Dierk Niessing

Research Interests

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Articles (13)

Inherited PURA Pathogenic Variant Associated With a Mild Neurodevelopmental Disorder

Crystal structure of the RNA-recognition motif of Drosophila melanogaster tRNA (uracil-5-)-methyltransferase homolog A

PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association

Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies

Human TRMT2A methylates tRNA and contributes to translation fidelity

Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging

Presence and function of Hbl B’, the fourth protein component encoded by the hbl operon in Bacillus cereus

Crystal structure of natural product argyrin-D determined by 3D electron diffraction

A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria

Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS

Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts

The large family of PC4-like domains – similar folds and functions throughout all kingdoms of life

Structural basis for the recognition of transiently structured AU-rich elements by Roquin

Collaborators (10)

Oliver Binas

Tim Gruene

Erwin Märtlbauer

Ejona Rusha

Michael Hildebrand

Ilaria Testa

Himanshu Goel

Andriy Chmyrov

Ingrid Scheffer

Kathi Zarnack

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