Dimitar Efremov

Head of Molecular Hematology

Institute of Genetic and Molecular and Cellular Biology

Italy

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About

Dimitar Efremov is the Head of Molecular Hematology at the International Center for Genetic Engineering and Biotechnology in Italy. His research focuses on the molecular mechanisms underlying hematologic malignancies, particularly chronic lymphocytic leukaemia and diffuse large B-cell lymphoma. Recent studies include the regulation of cancer cell migration, the role of genetic and biological parameters in Richter Syndrome, and the enhancement of anti-tumor therapies.

Articles (10)

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2025

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

Collaborators (2)

Supriya Chakraborty

Research Assistant Professor

Levine Cancer Institute

UNITED STATES

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Silvia Deaglio

University of Turin

ITALY

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Dimitar Efremov

Research Interests

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Articles (10)

G-protein coupled receptor kinase-2 regulates the migration of chronic lymphocytic leukaemia cells to sphingosine-1 phosphate in vitro and their trafficking in vivo

Implications of Genetic, Biological and Clinical Parameters in Patients With Richter Syndrome: A Monocentric Experience

A molecular circuit linking the BCR to the NAD biosynthetic enzyme NAMPT is an actionable target in Richter syndrome

Molecular Subtypes and the Role of TP53 in Diffuse Large B-Cell Lymphoma and Richter Syndrome

Improvement of the anti-tumor activity of NK cells and the efficacy of antiCD20 monoclonal antibodies in the therapy of B cell-derived malignancies

Potassium/sodium cation carriers robustly upregulate CD20 antigen by targeting MYC and synergize with anti-CD20 immunotherapies to eliminate malignant B cells

Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia

Clinical and molecular features of familial chronic lymphocytic leukemia: a pilot monocentric study

Editorial: The notch signaling pathway in lymphoid malignancies

Macrophage- and BCR- but not TLR-derived signals support the growth of CLL and Richter Syndrome murine models in vivo

Collaborators (2)

Supriya Chakraborty

Silvia Deaglio

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