Dimitris Polychronopoulos

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Chief Data Officer and co-founder

CureCollect

United Kingdom

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About

Dimitris Polychronopoulos is the Chief Data Officer and co-founder at CureCollect in the UK. His research areas encompass cancer biology, particularly the resistance mechanisms in breast cancer and non-small cell lung cancer, as well as genomic studies related to rare diseases and neurodevelopmental disorders. He has authored several recent articles that focus on topics including tumour growth variability, the role of bioinformatics in COVID-19 research, and the genetic underpinnings of multisystem syndromes.

Recent Grants

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Computational Analyses of Conserved non-coding Elements

Open Date: 2013-01-01

Close Date: 2013-04-01

Articles (10)

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2024

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2024

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2024

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (17)

Meena Balasubramanian

University of Sheffield

UNITED KINGDOM

Dimitris Polychronopoulos

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Recent Grants

Articles (10)

Biallelic CRELD1 variants cause a multisystem syndrome including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections

Understanding tumour growth variability in breast cancer xenograft models identifies PARP inhibition resistance biomarkers

BioASQ Synergy: a dialogue between question-answering systems and biomedical experts for promoting COVID-19 research.

Genotype–phenotype correlations for COL4A3–COL4A5 variants resulting in Gly substitutions in Alport syndrome

Whole genome sequencing for the diagnosis of neurological repeat expansion disorders in the UK: a retrospective diagnostic accuracy and prospective clinical validation study.

Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer

Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis.

100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care - Preliminary Report.

A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy

Collaborators (17)

Meena Balasubramanian

Julius Jacobsen

Edward Tobias

Jesús Rodríguez Pascual

Nayana Lahiri

Lara Menzies

Sally Ann Lynch

Tom Fowler

James Buchanan

Caroline Wright

KATHERINE LACHLAN

Siddharth Banka

Serena Nik-Zainal

Michael Simpson

Jamie Ellingford

Beata S. Lipska-Ziętkiewicz

Huw Thomas

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