Diva D. De Leon

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Professor of Pediatrics

University of Pennsylvania

United States

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Recent Grants

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Development of novel prodrugs targeting Glutamate Dehydrogenase (GDH) for the treatment of congenital hyperinsulinemia disorder including Hyperinsulinemia-Hyperammonemia Syndrome (HHS) and SCHAD-HI.

Open Date: 2018-08-01

Close Date: 2020-07-31

Grant: Close

Congenital Hypoglycemia Disorders: Hyperinsulinism and Glycogen Storage Diseases

Open Date: 2016-04-13

Close Date: 2017-03-31

Grant: Close

Insulin Secretion in Hyperinsulinism Human Islets

Open Date: 2013-09-15

Close Date: 2023-12-31

Grant: Close

Phase 2A Study of Exendin for the Treatment of Congenital Hyperinsulinism

Open Date: 2013-05-01

Close Date: 2016-12-31

Grant: Close

Role of GLP-1 in Congenital Hyperinsulinism

Open Date: 2009-08-13

Close Date: 2013-06-30

Articles (17)

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2024

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2022

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2022

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2021

Collaborators (4)

Sarah Flanagan

Associate Professor of Genomic Medicine and Sir Henry Dale Fellow

University of Exeter

UNITED KINGDOM

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Lisa States

Associate Professor

Children's Hospital of Philadelphia

UNITED STATES

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Meghan Craven

Assistant Professor

Baylor College of Medicine

UNITED STATES

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Deborah Harris

Lecturer/Nurse Practitioner

Victoria University of Wellington

NEW ZEALAND

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Diva D. De Leon

Research Interests

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Contact this professor

Recent Grants

Articles (17)

Role of beta-hydroxybutyrate measurement in the evaluation of plasma glucose concentrations in newborn infants

Hyperinsulinemic Hypoglycemia Due to an Insulinoma in a 2-Year-Old Child

Approach to the Neonate With Hypoglycemia

The Birth Prevalence of Congenital Hyperinsulinism: A Narrative Review of the Epidemiology of a Rare Disease

Clinical and Molecular Characterization of Hyperinsulinism in Kabuki Syndrome

Characterization of the zebrafish as a model of ATP-sensitive potassium channel hyperinsulinism

Dasiglucagon for the Treatment of Congenital Hyperinsulinism: A Randomized Phase 3 Trial in Infants and Children

International Guidelines for the Diagnosis and Management of Hyperinsulinism

A selective nonpeptide somatostatin receptor 5 agonist effectively decreases insulin secretion in hyperinsulinism

Insulin Immunoassay Interference Due to Human Antimouse Antibodies in a Patient With Ketotic Hypoglycemia

Undiagnosed hypoglycaemia disorders in children detected when hypoglycaemia occurs in the setting of illness: a retrospective study

Congenital hyperinsulinism: localization of a focal lesion with 18F-FDOPA positron emission tomography

The Use of Lanreotide in the Treatment of Congenital Hyperinsulinism

Exendin-(9-39) Effects on Glucose and Insulin in Children With Congenital Hyperinsulinism During Fasting and During a Meal and a Protein Challenge

Incidence and risk factors for hypoglycemia during maintenance chemotherapy in pediatric acute lymphoblastic leukemia

Mosaic <b><i>GLUD1</i></b> Mutations Associated with Hyperinsulinism Hyperammonemia Syndrome

The Bihormonal Bionic Pancreas Improves Glycemic Control in Individuals With Hyperinsulinism and Postpancreatectomy Diabetes: A Pilot Study

Collaborators (4)

Sarah Flanagan

Lisa States

Meghan Craven

Deborah Harris

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