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Dorothea Dr. Alexander-Friedrich

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Head of the Research Laboratory

University of Tübingen

Germany

Research Interests

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Professors in Germany Professors in Tissue Engineering Tissue Engineering professors in Germany

Recent Grants

Grant: Close

iPS cell generation from jaw periosteum: is the resulting osteogenic capacity more efficient?

Open Date: 2017-01-01

Close Date: 2024-12-31

Grant: Close

Analysis for the development of tissue engineering constructs for the treatment of large mandible defects

Open Date: 2013-01-01

Close Date: 2014-12-31

Grant: Close

Verbundprojekt Gesundheitsregion REGiNA, Innovative Ersatzstoffe und Implantate mit autologen Knochenhautzellen für die Knochenregeneration

Open Date: 2010-04-01

Close Date: 2014-09-30

Grant: Close

Osteogenesis-activating biofunctionalization and mechanical stabilization of tricalcium phosphate tissue engineering constructs for bone defects

Open Date:

Close Date:

Grant: Close

Einfluss von Glucocorticoiden auf die extrazelluläre Matrix und die Mechanosensibilität von Osteoblasten

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Close Date:

Articles (16)

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2026

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2023

Collaborators (8)

Andreas K. Nussler

University of Tübingen

GERMANY

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António J. Salgado

Coordinating Investigator

University of Minho

PORTUGAL

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Víctor Carriel

Professor/Researcher

Universidad de Granada

SPAIN

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Marina Danalache

Lab Leader

Universitätsklinikum Tübingen

GERMANY

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Jaroslav Čapek

Senior scientist

FZU - Institute of Physics of the Czech Academy of Sciences

CZECH REPUBLIC

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Sabrina Ehnert

Researcher

Eberhard-Karls-Universität Tübingen Medizinische Fakultät

GERMANY

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Meltem Avci-Adali

Research Director

University Hospital Tübingen

GERMANY

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Kristian-Christos Ngamsri

University Hospital Tübingen

GERMANY

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Dorothea Dr. Alexander-Friedrich

Research Interests

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Recent Grants

Articles (16)

Corticosteroid-induced alterations in cytoskeletal organization and mechanosensing of osteoarthritic synoviocytes

Prolonged In Vitro Expansion Shapes the Neuro-Supportive Potential of Jaw Periosteum Secretomes: Implications for Secretome Product Quality

Multi-omics-informed hydrogel design: modulating IL-6 to reduce endoplasmic reticulum stress in bone regeneration

Response of human periosteal cells to degradation products of zinc and its alloy (vol 108, 110208, 2020)

Spatiotemporally Adaptive Bilayer Silk Fibroin-Polyvinyl Alcohol-Metformin Composite Coating on Biodegradable Zinc for Orthopedic Applications

Revitalizing the Epigenome of Adult Jaw Periosteal Cells: Enhancing Diversity in iPSC-Derived Mesenchymal Stem Cells (iMSCs)

Development of an Ex Vivo Osteochondral Biomimetic Platform for Mechanistic Investigation of Cartilage Regeneration

Inhibition of TGF-β signaling enhances osteogenic potential of iPSC-derived MSCs

Mechanosignaling in Osteoporosis: When Cells Feel the Force

A Simple Pit Assay Protocol to Visualize and Quantify Osteoclastic Resorption<i> In</i> Vitro (Jun 16, 10.3791/64016, 2022)

Mesenchymal Stem Cell Plasticity: What Role Do Culture Conditions and Substrates Play in Shaping Biomechanical Signatures?

Three-Dimensionally Cultured Jaw Periosteal Cells Attenuate Macrophage Activation of CD4<SUP>+</SUP> T Cells and Inhibit Osteoclastogenesis

Zinc based biodegradable metals for bone repair and regeneration: Bioactivity and molecular mechanisms

Increased Levels of BAMBI Inhibit Canonical TGF-β Signaling in Chronic Wound Tissues

Secretomes derived from osteogenically differentiated jaw periosteal cells inhibit phenotypic and functional maturation of CD14+ monocyte-derived dendritic cells

Mechanical and Functional Improvement of β-TCP Scaffolds for Use in Bone Tissue Engineering

Collaborators (8)

Andreas K. Nussler

António J. Salgado

Víctor Carriel

Marina Danalache

Jaroslav Čapek

Sabrina Ehnert

Meltem Avci-Adali

Kristian-Christos Ngamsri

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