How does ageing impact on neuroinflammation and blood-brain barrier function?

This PhD position at the University of Birmingham focuses on the blood-brain barrier (BBB), a complex vascular structure that separates the systemic circulation from the central nervous system (CNS). The BBB is composed of multiple cell types, including endothelial cells, pericytes, and astrocytes, which together provide both physical and functional separation between the blood and the brain. The project will investigate the cellular interactions and mechanisms that underlie BBB function and its role in maintaining CNS homeostasis. Students will have the opportunity to work in a multidisciplinary environment, utilizing advanced techniques in vascular biology, neurobiology, and cell physiology. The research aims to deepen understanding of how the BBB regulates the movement of molecules and cells between the blood and the brain, with implications for neurological health and disease. The University of Birmingham offers a vibrant research community and access to state-of-the-art facilities. Funding details and specific entry requirements are not provided in the current description. Interested candidates should monitor the university's application portal for updates on eligibility criteria and application procedures.