Dr. SAMANTHA SHARMA

Assistant Research Professor

Indiana State University

United States

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Dr. Samantha Sharma is an Assistant Research Professor at Indiana University, USA. Her research focuses on immunology and cancer therapies, with recent articles addressing topics such as M2 macrophage polarization, Treg cell reprogramming for cancer immunotherapy, and the molecular mechanisms involved in the response to environmental factors like diesel exhaust exposure. Additionally, she explores genetic adaptations to high-altitude living and contributes insights into clinical trials for immune checkpoint inhibitors in colorectal cancer.

Articles (15)

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2025

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2020

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2020

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2020

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2020

Collaborators (6)

Xusheng Wang

North Dakota State University

UNITED STATES

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Mateusz Opyrchal

Associate Professor

Indiana University School of Medicine

UNITED STATES

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Jun Wan

Adjunct Associate Professor

Indiana University-Purdue University Indianapolis

UNITED STATES

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Xiongbin Lu

UNITED STATES

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Tao Yu

Indiana University Bloomington

UNITED STATES

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Xiumei Huang

Assistant Professor

Indiana University School of Medicine

UNITED STATES

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Dr. SAMANTHA SHARMA

Research Interests

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Articles (15)

Reprogramming intratumoral Treg cells by morpholino-mediated splicing of FOXP3 for cancer immunotherapy

STK11 coordinates IL-4 signaling with metabolic reprogramming to control M2 macrophage polarization and antitumor immunity

Molecular and Immunological Mechanisms Associated with Diesel Exhaust Exposure

Chasing genes at high‐altitude

Editorial on “Characteristics and risk profiles of patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension living permanently at >2500 m of high altitude in Ecuador”

Hypobaric hypoxia drives selection of altitude-associated adaptative alleles in the Himalayan population

Molecular insights into clinical trials for immune checkpoint inhibitors in colorectal cancer: Unravelling challenges and future directions

Photo-activated microtubule targeting drugs: Advancing therapies for colorectal cancer

A T Cell-Engaging Tumor Organoid Platform for Pancreatic Cancer Immunotherapy.

BET inhibition targets ABC-DLBCL constitutive B-cell receptor signaling through PAX5

Harnessing tumorous flaws for immune supremacy: is miRNA-155 the weak link in breast cancer progression?

DNA Damage and Repair in Pulmonary Arterial Hypertension

DNA Damage and Repair in Pulmonary Arterial Hypertension

Slide-Seq for Spatially Mapping Gene Expression. Metabolic Syndrome Exacerbates Group 2 Pulmonary Hypertension, and NAD Metabolism Is Influenced by Tissue Origin.

Rodriques SG, et al. Slide-Seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution. Science (1)

Collaborators (6)

Xusheng Wang

Mateusz Opyrchal

Jun Wan

Xiongbin Lu

Tao Yu

Xiumei Huang

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