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Eain Murphy

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Professor

SUNY Upstate Medical University

United States

Research Interests

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Professors in United States Professors in Immunology Immunology professors in United States

Recent Grants

Grant: Close

Alzheimer's Disease associated pathology induced by neurotropic viral infection

Open Date: 2021-09-30

Close Date: 2026-08-31

Grant: Close

Antiviral responses of host mediated S-nitrosylation of viral proteins.

Open Date: 2021-03-23

Close Date: 2026-02-28

Grant: Close

Biological functions of beta herpesvirus encoded non-coding RNAs

Open Date: 2019-06-01

Close Date: 2022-05-31

Grant: Close

Mechanisms of Human Cytomegalovirus Latency

Open Date: 2013-08-01

Close Date: 2018-07-31

Grant: Close

Mutational Analysis of Recently Identified Human Cytomegalovirus ORFs

Open Date: 2005-02-01

Close Date: 2007-04-30

Articles (11)

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2025

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2023

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2023

Collaborators (10)

Jimmy D. Dikeakos

University of Western Ontario

CANADA

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Chandrav De

Senior Scientist

Wyss Institute for Biologically Inspired Engineering

UNITED STATES

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Bruce Banfield

Queen's University

CANADA

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Stephen Mark Tompkins

University of Georgia

UNITED STATES

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Matthew Reeves

Reader/Associate Professor of Molecular Virology

University College London

UNITED KINGDOM

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Luis Maria Schang

Professor

Cornell University College of Veterinary Medicine

UNITED STATES

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Karl Munger

Professor

Tufts University

UNITED STATES

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Gary C. Chan

SUNY Upstate Medical University

UNITED STATES

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Ian Groves

Assistant Professor

Cleveland Clinic

UNITED STATES

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Dohun Pyeon

MSU Foundation Distinguished Professor

Michigan State University

UNITED STATES

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Eain Murphy

Research Interests

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Recent Grants

Articles (11)

Protein-S-nitrosylation of adenovirus-5 E1A and human papillomavirus 16 E7 limits their ability to inhibit STING activity

Generation of a panel of mutants that are resistant to standard of care therapies in a clinically relevant strain of human cytomegalovirus for drug resistance profiling.

Protein-S-nitrosylation of human cytomegalovirus pp65 reduces its ability to undermine cGAS

Herpes simplex virus-1 infection alters microtubule-associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease.

Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo.

The effective multiplicity of infection for HCMV depends on the activity of the cellular 20S proteasome

Herpes simplex virus-1 targets the 2'-3'cGAMP importer SLC19A1 as an antiviral countermeasure.

Import of extracellular 2'-3'cGAMP by the folate transporter, SLC19A1, establishes an antiviral response that limits herpes simplex virus-1.

The Human Cytomegalovirus Latency-Associated Gene Product Latency Unique Natural Antigen Regulates Latent Gene Expression

Virology under the Microscope-a Call for Rational Discourse.

An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity.

Collaborators (10)

Jimmy D. Dikeakos

Chandrav De

Bruce Banfield

Stephen Mark Tompkins

Matthew Reeves

Luis Maria Schang

Karl Munger

Gary C. Chan

Ian Groves

Dohun Pyeon

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