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Edda G Schulz

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Max Planck Research Group Leader

Max Planck Institute for Molecular Genetics

Germany

Research Interests

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Recent Grants

Grant: Close

Architectural Rearrangements at the Xist locus during the onset of X-chromosome inactivation

Open Date: 2022-01-01

Close Date:

Grant: Close

Regulatory Logic, Thresholds and Epigenetic Memory: How cis-regulatory landscapes tune gene activity during mammalian development

Open Date: 2021-08-01

Close Date: 2026-07-31

Grant: Close

GRK 2403: Dissecting and Reengineering the Regulatory Genome

Open Date: 2019-01-01

Close Date: 2023-12-31

Grant: Close

Towards a quantitative understanding of the mechanistic coupling of X-inactivation and pluripotency

Open Date: 2018-05-01

Close Date: 2021-04-30

Grant: Close

The interplay of trans and cis-acting elements during initiation of random X-chromosome inactivation

Open Date: 2010-05-01

Close Date: 2013-04-30

Articles (11)

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2025

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

Collaborators (2)

Philipp Voigt

Tenure-Track Group Leader

Babraham Institute

UNITED KINGDOM

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Teresa Rayon

Group Leader

Babraham Institute

UNITED KINGDOM

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Edda G Schulz

Research Interests

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Recent Grants

Articles (11)

Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus

mTOR activity paces human blastocyst stage developmental progression

Structural remodeling of the inactive X chromosome during early mouse development.

Establishment and maintenance of random monoallelic expression.

Spatial orchestration of the genome: topological reorganisation during X-chromosome inactivation.

BREACHing new grounds in fragile X syndrome: Trinucleotide expansion linked to genome-wide heterochromatin domains and genome misfolding.

GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers.

Epigenetic dynamics during capacitation of naïve human pluripotent stem cells.

Modeling unveils sex differences of signaling networks in mouse embryonic stem cells.

CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression.

Regulatory principles and mechanisms governing the onset of random X-chromosome inactivation.

Collaborators (2)

Philipp Voigt

Teresa Rayon

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