Eddie Wang

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Professor

Cardiff University School of Medicine

United Kingdom

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About

Professor Eddie Wang is a faculty member at Cardiff University School of Medicine in the UK. His research primarily focuses on virology and immunology, with recent publications addressing topics such as immune evasion by Human Cytomegalovirus, host interactions in SARS-CoV-2 infections, and the role of various cytokines and receptors in immune responses. His work contributes to a deeper understanding of natural killer cell function and the mechanisms behind antiviral defenses.

Recent Grants

Grant: Open

Generating killer cells for immunotherapy against cancer and pathogens

Open Date: 2023-10-01

Close Date: 2027-09-01

Grant: Close

Identifying risk factors in kidney transplant patients for disease caused by human cytomegalovirus infection

Open Date: 2022-10-01

Close Date: 2025-03-01

Grant: Close

The immunologic and virologic determinants of long COVID

Open Date: 2021-07-16

Close Date: 2023-07-31

Grant: Close

Characterisation of a novel class of natural killer cell immunoevasin

Open Date: 2021-04-30

Close Date: 2024-04-29

Grant: Close

A UK underpinning platform to study immunology and immunopathology of COVID-19:The UK Coronavirus Immunology Consortium

Open Date: 2020-08-19

Close Date: 2021-12-19

Articles (12)

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2020

Collaborators (25)

Laurence McEvoy

University of Liverpool

UNITED KINGDOM

Eddie Wang

Research Interests

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About

Recent Grants

Articles (12)

Human Cytomegalovirus Immune Evasion of Natural Killer Cells: A Virus for All Seasons?

Downregulation of endogenous nectin1 in human keratinocytes by herpes simplex virus 1 glycoprotein D excludes superinfection but does not affect NK cell function

Combined anti-S1 and anti-S2 antibodies from hybrid immunity elicit potent cross-variant ADCC against SARS-CoV-2

The cytokine receptor DR3 identifies and promotes the activation of thymic NKT17 cells

An Optimized CRISPR/Cas9 Adenovirus Vector (AdZ-CRISPR) for High-Throughput Cloning of sgRNA, Using Enhanced sgRNA and Cas9 Variants

Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex

CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis

SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies

Concerns over functional experiments, interpretation, and required controls.

A prenylated dsRNA sensor protects against severe COVID-19

Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus.

CD57+ Memory T Cells Proliferate In Vivo

Collaborators (25)

Laurence McEvoy

Gavin Wilkinson

Ian Humphreys

Kristin Ladell

Can Li

Jeffrey Y. Lee

Ruth Jarrett

Martin Potts

Rebecca Jensen

Elise Rees

Matthias Eberl

Joseph Hughes

Matthew Turnbull

Duncan M Baird

Rute Maria Pinto

Michael P. Weekes

Vanessa Herder

Richard Stanton

Ilan Davis

Angie Fawkes

Ceri Fielding

Marko Noerenberg

Leah Mary Hunter

Blair L. Strang

Margus Varjak

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