Efstratios Stratikos

Associate Professor

National and Kapodistrian University of Athens

Greece

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About

Efstratios Stratikos is an Associate Professor at the National and Kapodistrian University of Athens, Greece. His research focuses on the enzymatic mechanisms and regulation of aminopeptidases, specifically insulin-regulated aminopeptidase and its allosteric inhibitors. He has contributed to the discovery of novel compounds that enhance our understanding of cellular processes and the immunopeptidome.

Articles (14)

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2025

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (4)

Dimitris Georgiadis

National and Kapodistrian University of Athens

GREECE

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Anastasia Mpakali

National Centre for Scientific Research-Demokritos

GREECE

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Petros Giastas

Agricultural University of Athens

GREECE

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Lawrence Stern

Professor

University of Massachusetts Chan Medical School

UNITED STATES

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Efstratios Stratikos

Research Interests

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About

Articles (14)

Discovery of Novel Allosteric Inhibitor Hits for Insulin-Regulated Aminopeptidase Provides Insights on Enzymatic Mechanism

Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase

Stabilization of the open conformation οf insulin‐regulated aminopeptidase by a novel substrate‐selective small‐molecule inhibitor

Library screening identifies commercial drugs as potential structure correctors of abnormal apolipoprotein A-I

Author Correction: Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

Distinct modulation of cellular immunopeptidome by the allosteric regulatory site of ER aminopeptidase 1

Phosphinic Peptides as Tool Compounds for the Study of Pharmacologically Relevant Zn-Metalloproteases

Inhibitor-Dependent Usage of the S1′ Specificity Pocket of ER Aminopeptidase 2

ERAP2 Inhibition Induces Cell-Surface Presentation by MOLT-4 Leukemia Cancer Cells of Many Novel and Potentially Antigenic Peptides

Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

Discovery of Selective Inhibitor Leads by Targeting an Allosteric Site in Insulin-Regulated Aminopeptidase

A Carbodiimide-Mediated P–C Bond-Forming Reaction: Mild Amidoalkylation of P-Nucleophiles by Boc-Aminals

The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor Immunotherapy

Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein

Collaborators (4)

Dimitris Georgiadis

Anastasia Mpakali

Petros Giastas

Lawrence Stern

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