Elena Frolova

Professor

The University of Alabama

United States

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Professor Elena Frolova is a faculty member at the University of Alabama at Birmingham, USA. Her research focuses on virology, particularly the interactions of alphaviruses and SARS-CoV-2 with host cells, as well as the structural and functional characterization of viral proteins. Recent publications highlight her investigations into protein expression optimization, mechanisms of viral entry and infectivity, and the impact of mutations on viral replication.

Articles (9)

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2023

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2023

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2023

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (2)

Todd Green

University of Alabama, Tuscaloosa

UNITED STATES

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Ilya Frolov

The University of Alabama

UNITED STATES

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Elena Frolova

Research Interests

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Articles (9)

All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein

Alphavirus-based replicons demonstrate different interactions with host cells and can be optimized to increase protein expression

Alphavirus-induced transcriptional and translational shutoffs play major roles in blocking the formation of stress granules

Acquisition of Furin Cleavage Site and Further SARS-CoV-2 Evolution Change the Mechanisms of Viral Entry, Infection Spread, and Cell Signaling

Natural and Recombinant SARS-CoV-2 Isolates Rapidly Evolve In Vitro to Higher Infectivity through More Efficient Binding to Heparan Sulfate and Reduced S1/S2 Cleavage

Novel NMR Assignment Strategy Reveals Structural Heterogeneity in Solution of the nsP3 HVD Domain of Venezuelan Equine Encephalitis Virus

Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein

Hypervariable Domain of nsP3 of Eastern Equine Encephalitis Virus Is a Critical Determinant of Viral Virulence

Mutations in Hypervariable Domain of Venezuelan Equine Encephalitis Virus nsP3 Protein Differentially Affect Viral Replication

Collaborators (2)

Todd Green

Ilya Frolov

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