Eleonora Leucci

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Associate Professor

KU Leuven

Belgium

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About

Eleonora Leucci is an Associate Professor at KU Leuven in Belgium. Her research focuses on resistance mechanisms in melanoma, exploring topics such as cancer drug-tolerant persister cells, the effects of lipid polyunsaturation, and the role of non-coding RNAs. She has contributed significantly to the understanding of therapeutic vulnerabilities in BRAFi-resistant melanoma and the characterization of advanced cancer models for personalized treatment.

Recent Grants

Grant: Close

Role of MrT in cutaneous melanoma

Open Date: 2019-01-01

Close Date: 2022-01-01

Grant: Close

Treating melanoma as an infectious disease

Open Date: 2018-10-01

Close Date: 2022-09-01

Grant: Close

TRACE: a Belgian PDX platform facilitating cutting edge cancer research

Open Date: 2018-08-01

Close Date: 2021-07-01

Grant: Close

LncRNAs as modulators of protein synthesis rewiring in melanoma

Open Date: 2018-06-01

Close Date: 2021-05-31

Grant: Close

An oncogenomics-driven in vivo screen for long noncoding RNAs that modulate melanoma progression and metastasis

Open Date: 2013-02-01

Close Date: 2016-10-01

Articles (12)

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Year:

2021

Collaborators (16)

Bernard Gallez

BELGIUM

Eleonora Leucci

Research Interests

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About

Recent Grants

Articles (12)

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

Cancer drug-tolerant persister cells: from biological questions to clinical opportunities

Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy.

Hyperpolarized 13C-Pyruvate to Assess Response to Anti-PD1 Immune Checkpoint Inhibition in YUMMER 1.7 Melanoma Xenografts

The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma

Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA.

The AhR‐SRC axis as a therapeutic vulnerability in BRAFi‐resistant melanoma

Editorial: Role of mitochondria-associated non-coding RNAs in intracellular communication.

LncRNAs in human cancers: signal from noise

Establishment and Characterization of Advanced Penile Cancer Patient-derived Tumor Xenografts: Paving the Way for Personalized Treatments.

The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival.

Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivo

Collaborators (16)

Bernard Gallez

Frank Vernaillen

Mariangela Russo

Ginevra Doglioni

Pieter Mestdagh

Eric BARREY

fabio sparatore

Anna Sparatore

Tiziana Bonaldi

Frédéric Amant

Sébastien CORRE

Bénédicte F. Jordan

Caroline Bouzin

Celine Everaert

Kaat Durinck

Gabriel Malouf

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