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Elka R. Georgieva

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Assistant Professor and PI

Texas Tech University

United States

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About

Elka R. Georgieva is an Assistant Professor and Principal Investigator at Texas Tech University, located in the United States. Her research focuses on structural studies of small membrane proteins, the interactions of viral proteins with cellular membranes, and the engineering of heterologous transmembrane protein constructs. Recent publications include investigations into the conformations and oligomeric structures of various proteins, utilizing biochemical and biophysical approaches to enhance our understanding of protein dynamics and drug resistance mechanisms.

Recent Grants

Grant: Close

Production and reconstitution in lipid nanoparticles of the Mtb EfpA exporter

Open Date: 2023-01-01

Close Date: 2024-01-01

Grant: Close

Production and functional characterization of the L-lysine exporters from bacterial pathogens

Open Date: 2018-01-01

Close Date: 2020-01-01

Articles (10)

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2021

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2020

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2020

Collaborators (1)

Arvin Saffarian Delkhosh

Graduate Research and Teaching Assistant

Texas Tech University

UNITED STATES

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Elka R. Georgieva

Research Interests

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About

Recent Grants

Articles (10)

Conformations of influenza A M2 protein in DOPC/DOPS and E. coli native lipids and proteins

Engineered Chimera Protein Constructs to Facilitate the Production of Heterologous Transmembrane Proteins in <i>E. coli</i>

Highly versatile small virus-encoded proteins in cellular membranes: A structural perspective on how proteins' inherent conformational plasticity couples with host membranes' properties to control cellular processes.

HIV-1 Vpu protein forms stable oligomers in aqueous solution via its transmembrane domain self-association

Insights into the oligomeric structure of the HIV-1 Vpu protein

Production of recombinant Mtb membrane efflux pump for structural and functional studies to reveal mechanisms of drug resistance

Protein engineering and biochemical/biophysical approaches for structural studies of small membrane proteins and their complexes: Application to viroporins

Lipid Membrane Mimetics in Functional and Structural Studies of Integral Membrane Proteins.

Protein Conformational Dynamics upon Association with the Surfaces of Lipid Membranes and Engineered Nanoparticles: Insights from Electron Paramagnetic Resonance Spectroscopy.

High-yield production in E. coli and characterization of full-length functional p13<sup>II</sup> protein from human T-cell leukemia virus type 1.

Collaborators (1)

Arvin Saffarian Delkhosh

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