Elsa Yan

Professor

Yale University

United States

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Professor Elsa Yan is a faculty member at Yale University in the United States. Her research focuses on the interactions between water, biomolecules, and interfaces, exploring topics such as hydration shell structures and chiral spectroscopy. Recent publications highlight her work on drug binding in relation to DNA hydration and the implications of phase separation in biological contexts.

Articles (12)

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2020

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2020

Collaborators (2)

Sharon Hammes-Schiffer

Sterling Professor of Chemistry

Yale University

UNITED STATES

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Luis Velarde

Associate Professor

University at Buffalo

UNITED STATES

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Elsa Yan

Research Interests

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Articles (12)

Drug binding disrupts chiral water structures in the DNA first hydration shell

Beyond the “spine of hydration”: Chiral SFG spectroscopy detects DNA first hydration shell and base pair structures

Water-protein interactions as a driver of phase separation, biology, and disease

Theoretical basis for interpreting heterodyne chirality-selective sum frequency generation spectra of water

Characterizing Interfaces by Voronoi Tessellation

Design of an Electrostatic Frequency Map for the NH Stretch of the Protein Backbone and Application to Chiral Sum Frequency Generation Spectroscopy

Detecting Interplay of Chirality, Water, and Interfaces for Elucidating Biological Functions

Detecting the First Hydration Shell Structure around Biomolecules at Interfaces

Chiral Sum Frequency Generation Spectroscopy Detects Double-Helix DNA at Interfaces

Simulation of the Chiral Sum Frequency Generation Response of Supramolecular Structures Requires Vibrational Couplings

Mirror-image antiparallel β-sheets organize water molecules into superstructures of opposite chirality

Impact of the Emergency Transition to Remote Teaching on Student Engagement in a Non-STEM Undergraduate Chemistry Course in the Time of COVID-19

Collaborators (2)

Sharon Hammes-Schiffer

Luis Velarde

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