Emmanuel Pinteaux

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The University of Manchester

United Kingdom

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Recent Grants

Grant: Close

Interleukin-1 alpha as a novel treatment for ischemic stroke

Open Date: 2018-07-01

Close Date: 2023-05-31

Grant: Close

Mesenchymal stem cells preconditioning as therapeutic tool to promote recovery from stroke

Open Date: 2017-09-01

Close Date: 2020-09-01

Grant: Close

The role of extracellular matrix laminin-10 in vascular inflammation, blood-brain barrier repair and angiogenesis after cerebrovascular disease

Open Date: 2017-04-01

Close Date: 2020-03-31

Grant: Close

Use of IL-1alpha to Promote Angiogenesis and Functional Recovery After Experimental Stroke

Open Date: 2014-07-01

Close Date: 2016-06-30

Grant: Close

Use of IL-1alpha to Promote Angiogenesis and Functional Recovery After Experiment

Open Date: 2014-07-01

Close Date: 2016-06-30

Articles (16)

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2025

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2020

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2020

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2020

Collaborators (19)

Rachel Lennon

The University of Manchester

UNITED KINGDOM

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Lewis Quayle

Senior Lecturer in Data Science and Analytics

Sheffield Hallam University

UNITED KINGDOM

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Neil Humphreys

Head of Gene Editing and Embryology Facility

ITALY

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Musa Mhlanga

Professor

Radboud Universiteit Nijmegen Radboud Institute for Molecular Life Sciences

NETHERLANDS

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Alba Grayston

University of Manchester

UNITED KINGDOM

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Paul R. Kasher

The University of Manchester

UNITED KINGDOM

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Corinne Tanchot

Université Paris Cité

FRANCE

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Catriona Cunningham

University of Aberdeen

UNITED KINGDOM

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Ziad Mallat

University of Cambridge

UNITED KINGDOM

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Helen Parker

The University of Manchester

UNITED KINGDOM

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Soraya Taleb

DR (directeur de Recherche)/Research professor

INSERM

FRANCE

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Catherine Lawrence

Senior Lecturer

The University of Manchester

UNITED KINGDOM

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Hafid Ait-Oufella

Université Paris-Saclay

FRANCE

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Josephine Thomas

The University of Manchester

UNITED KINGDOM

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Stephane Potteaux

Université de Reims Champagne-Ardenne

FRANCE

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Stuart Allan

Professor of Neuroscience

The University of Manchester

UNITED KINGDOM

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Morgan Salmon

University of Michigan

UNITED STATES

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Jessica Millar

University of Michigan

UNITED STATES

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Hannah Thurgur

Imperial College London

UNITED KINGDOM

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Emmanuel Pinteaux

Research Interests

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Recent Grants

Articles (16)

Loss of col4a1 in zebrafish recapitulates the cerebrovascular phenotypes associated with monogenic cerebral small vessel disease

Selective deletion of interleukin-1 alpha in microglia does not modify acute outcome but may regulate neurorepair processes after experimental ischemic stroke

Endothelial to mesenchymal transition in the interleukin-1 pathway during aortic aneurysm formation

Hypoxia and interleukin-1-primed mesenchymal stem/stromal cells as novel therapy for stroke

Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming

Preconditioning with interleukin-1 alpha is required for the neuroprotective properties of mesenchymal stem cells after ischaemic stroke in mice

Intracerebral administration of a novel self-assembling peptide hydrogel is safe and supports cell proliferation in experimental intracerebral haemorrhage

Endothelial cell activation by interleukin-1 and extracellular matrix laminin-10 occurs via the YAP signalling pathway.

Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6C<sup>hi</sup> monocytes and differentiation to pro-angiogenic myeloid cells.

Regenerative Potential of Hydrogels for Intracerebral Hemorrhage: Lessons from Ischemic Stroke and Traumatic Brain Injury Research

IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer.

Neurogenesis After Stroke: A Therapeutic Perspective

Cell-specific conditional deletion of interleukin-1 (IL-1) ligands and its receptors: a new toolbox to study the role of IL-1 in health and disease

Neuroinflammation and fibrosis in stroke: The good, the bad and the ugly.

Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA

The therapeutic potential of extracellular vesicles in preclinical stroke models: a systematic review and meta-analysis

Collaborators (19)

Rachel Lennon

Lewis Quayle

Neil Humphreys

Musa Mhlanga

Alba Grayston

Paul R. Kasher

Corinne Tanchot

Catriona Cunningham

Ziad Mallat

Helen Parker

Soraya Taleb

Catherine Lawrence

Hafid Ait-Oufella

Josephine Thomas

Stephane Potteaux

Stuart Allan

Morgan Salmon

Jessica Millar

Hannah Thurgur

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