Eric Defrancq

Professeur

Université Grenoble Alpes

France

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Eric Defrancq is a Professor at Université Grenoble Alpes in France. His research focuses on biophysical evaluations of G-quadruplexes, small-molecule ligands of telomeric DNA, and the development of innovative detection methods for DNA structures. Recent articles include studies on luminescent complexes, conformational transitions in DNA, and the impact of molecular interactions in cancer cell environments.

Articles (11)

Year:

2024

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

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2021

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Collaborators (5)

Anton Granzhan

PSL Research University

FRANCE

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Anabelle Decottignies

Principal investigator, Professor

Université catholique de Louvain

BELGIUM

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Angéline VAN DER HEYDEN

Assistant Professor

Université Grenoble Alpes

FRANCE

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Jérôme DEJEU

Assistant Professor

Université Grenoble Alpes

FRANCE

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Jean-Francois Poissson

Professeur

Université Grenoble Alpes

FRANCE

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Eric Defrancq

Research Interests

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Contact this professor

About

Articles (11)

Systematic Evaluation of Benchmark G4 Probes and G4 Clinical Drugs using three Biophysical Methods: A Guideline to Evaluate Rapidly G4‐Binding Affinity

Luminescent Ruthenium(II) Complexes Used for the Detection of 8-Oxoguanine in the Human Telomeric Sequence

Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences

Assessment of presumed small-molecule ligands of telomeric i-DNA by biolayer interferometry (BLI)

Conformational transition in SPR experiments: impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude

Photo-induced telomeric DNA damage in human cancer cells

Constrained G4 structures unveil topology specificity of known and new G4 binding proteins

Negative SPR Signals during Low Molecular Weight Analyte Recognition

Flexible RuII Schiff Base Complexes: G‐Quadruplex DNA Binding and Photo‐Induced Cancer Cell Death

Direct Detection of Low-Molecular-Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry

Redox-Active Bis-Cyclometalated Iridium(III) Complex as a DNA Photo-Cleaving Agent

Collaborators (5)

Anton Granzhan

Anabelle Decottignies

Angéline VAN DER HEYDEN

Jérôme DEJEU

Jean-Francois Poissson

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