Eric Gamazon

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University of Chicago

United States

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Recent Grants

Grant: Open

ECHO Laboratory Core at Vanderbilt for Integrated Sample Biobanking and Processing

Open Date: 2023-09-01

Close Date: 2030-05-01

Grant: Open

Gene Expression Regulation in Brains of East Asian, African, and European Descent Explains Schizophrenia GWAS in Diverse Populations

Open Date: 2022-03-01

Close Date: 2027-01-01

Grant: Close

Advancing drug repositioning and development for Alzheimer's Disease using functional genomics and computational phenomics

Open Date: 2021-09-01

Close Date: 2024-08-01

Grant: Close

Integrative analysis of multiomic datasets for discovery of molecular underpinnings of large-scale human brain networks

Open Date: 2021-09-01

Close Date: 2024-09-01

Grant: Close

Haplotype-aware models of gene and isoform expression with application to genetic studies of disease in diverse populations

Open Date: 2021-03-01

Close Date: 2024-11-01

Articles (30)

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Collaborators (24)

Valeria Lo Faro

University Medical Center Groningen

NETHERLANDS

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Juulia Partanen

University of Helsinki

FINLAND

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Mario Falchi

King’s College London

UNITED KINGDOM

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Andrew S. Perry

Vanderbilt University Medical Center

UNITED STATES

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Priit Palta

University of Helsinki

FINLAND

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Ramon Viñas

EPFL

SWITZERLAND

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Ruth Loos

Københavns Universitet

DENMARK

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Marta Garcia-Contreras

University of Miami School of Medicine

UNITED STATES

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Gokhan Unlu

Rockefeller University

UNITED STATES

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Tian Ge

Broad Institute

UNITED STATES

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Wole Akosile

AUSTRALIA

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Nathan Tucker

Masonic Medical Research Institute

UNITED STATES

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Eske Derks

Professor

QIMR Berghofer Medical Research Institute

AUSTRALIA

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Nomdo M. Jansonius

NETHERLANDS

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Heather M Highland

University of North Carolina at Chapel Hill

UNITED STATES

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Eric Farber-Eger

Vanderbilt University Medical Center

UNITED STATES

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Ying Wang

University of Groningen

NETHERLANDS

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Arjun Bhattacharya

Assistant Professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Sini Kerminen

University of Helsinki

FINLAND

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Sarah Finer

Clinical Reader in Diabetes

Queen Mary University of London

UNITED KINGDOM

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Kivanc Birsoy

Rockefeller University

UNITED STATES

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Quanhu Sheng

Assistant Professor

Vanderbilt University Medical Center

UNITED STATES

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Jonathan Emberson

Professor of Medical Statistics and Epidemiology

University of Oxford

UNITED KINGDOM

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Jukka Koskela

University of Helsinki

FINLAND

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Eric Gamazon

Research Interests

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Recent Grants

Articles (30)

Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure

Multiomics of Human Obesity and Related Multisystem Diseases

Integrating population-level and cell-based signatures for drug repositioning

Transcriptome-wide root causal inference

First clinical diagnosis of FAME3 via commercial Long-Read sequencing reveals mosaic repeat expansion in MARCHF6 gene

Genetic analysis in African ancestry populations reveals genetic contributors to lung cancer susceptibility

Plasma Proteomic Signatures for Diverticulitis Risk Stratification

The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity

Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes

Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits

Integration of estimated regional gene expression with neuroimaging and clinical phenotypes at biobank scale

Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure

A multi-modal framework improves prediction of tissue-specific gene expression from a surrogate tissue

Metabolic gene function discovery platform GeneMAP identifies SLC25A48 as necessary for mitochondrial choline import

Transcriptome-wide association study and Mendelian randomization in pancreatic cancer identifies susceptibility genes and causal relationships with type 2 diabetes and venous thromboembolism

Genetic correlation and causal associations between psychiatric disorders and lung cancer risk

A transcriptomic atlas of the human brain reveals genetically determined aspects of neuropsychiatric health.

A deep catalogue of protein-coding variation in 983,578 individuals.

Transcriptome analysis of cardiac endothelial cells after myocardial infarction reveals temporal changes and long-term deficits.

The broad impact of cell death genes on the human disease phenome

Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts.

Identification of drug repurposing candidates for the treatment of anxiety: A genetic approach

Hypergraph factorization for multi-tissue gene expression imputation

Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals

Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome.

Towards mechanistic models of mutational effects: Deep learning on Alzheimer’s Aβ peptide

Global Biobank Meta-analysis Initiative

Rare and common genetic determinants of metabolic individuality and their effects on human health

IMMerge: Merging imputation data at scale.

Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: Lessons from the Global Biobank Meta-analysis Initiative.

Collaborators (24)

Valeria Lo Faro

Juulia Partanen

Mario Falchi

Andrew S. Perry

Priit Palta

Ramon Viñas

Ruth Loos

Marta Garcia-Contreras

Gokhan Unlu

Tian Ge

Wole Akosile

Nathan Tucker

Eske Derks

Nomdo M. Jansonius

Heather M Highland

Eric Farber-Eger

Ying Wang

Arjun Bhattacharya

Sini Kerminen

Sarah Finer

Kivanc Birsoy

Quanhu Sheng

Jonathan Emberson

Jukka Koskela

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