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Erica Weekman

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Assistant Research Professor

Indiana University School of Medicine

United States

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Recent Grants

Grant: Close

Establishing the role of MMP9 in amyloid-immunotherapy-induced ARIA

Open Date: 2022-09-15

Close Date: 2025-08-31

Grant: Open

Strategies for targeting astrocyte reactivity in Alzheimer's disease and related dementias

Open Date: 2022-09-01

Close Date: 2027-06-30

Grant: Close

Elucidating the role of placental growth factor in diffuse white matter disease

Open Date: 2020-04-01

Close Date: 2026-03-31

Grant: Close

Evaluation of pathologies associated with hyperhomocysteinemia in human autopsy brain tissue

Open Date: 2019-07-01

Close Date: 2020-06-01

Grant: Close

Therapeutic targeting of TREM2 for Alzheimer's disease

Open Date: 2018-04-01

Close Date: 2023-03-31

Articles (14)

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2026

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2023

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2023

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2023

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2023

Collaborators (7)

Shawn N. Whitehead

Western University

CANADA

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Timothy Sampson

Asst. Professor

Emory University School of Medicine

UNITED STATES

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Donna Wilcock

Professor

University of Kentucky

UNITED STATES

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Sami Case

Assistant Professor

Colorado State University

UNITED STATES

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Madelyn Houser

Research Assistant Professor

Emory University

UNITED STATES

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David Fardo

Professor

University of Kentucky

UNITED STATES

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Adam Bachstetter

Associate Professor

University of Kentucky

UNITED STATES

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Erica Weekman

Research Interests

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Recent Grants

Articles (14)

Full functional knockout of placental growth factor primes the mouse neurovasculature for inflammation and injury

Acute anti-Aβ antibody exposure induces microglial changes and significantly alters chemokine signaling.

Inhibition of astrocyte signaling leads to sex-specific changes in microglia phenotypes in a diet-based model of cerebral small vessel disease.

Age-related cerebral amyloid angiopathy accumulation in the APPSw mouse model is associated with perivascular inflammation and brain-wide vascular and inflammatory gene and protein changes.

The future of biomarkers for vascular contributions to cognitive impairment and dementia (VCID): proceedings of the 2025 annual workshop of the Albert research institute for white matter and cognition.

Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina.

Acute Communication Between Microglia and Nonparenchymal Immune Cells in the Anti-Aβ Antibody-Injected Cortex.

Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK‐ADRC cohort

Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease

Soluble TNF mediates amyloid-independent, diet-induced alterations to immune and neuronal functions in an Alzheimer’s disease mouse model

Mechanisms of ARIA: is it time to focus on the unique immune environment of the neurovascular unit?

Using digital pathology to analyze the murine cerebrovasculature.

Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.

Association between APOE genotype and microglial cell morphology.

Collaborators (7)

Shawn N. Whitehead

Timothy Sampson

Donna Wilcock

Sami Case

Madelyn Houser

David Fardo

Adam Bachstetter

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