Esther L. Moss
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IMPROVING ENDOMETRIAL CANCER SURVIVAL BY IDENTIFYING A HIGH-RISK MOLECULAR PROFILE
Open Date: 2016-07-01
Close Date: 2018-07-01
Grant: Close
Determinants of risk and prognosis in endometrial cancer
Open Date: 2015-11-01
Close Date: 2016-11-01
Articles (10)
Year:
2023
A longitudinal, descriptive, prospective, and prolective study of individuals with endometrial or cervical cancer/pre-cancer diagnoses and high BMI (over 35 kg/m2) undergoing RH was conducted. Of the 53 participants recruited, 3 (6%) were converted to open surgery. The 50 RH participants had median BMI 42 kg/m2 (range 35 to 60): the range 35–39.9 kg/m2 had 17 cases; the range 40–44.9 kg/m2 had 15 cases; 45–49.9 kg/m2 8 cases; and those ≥50 kg/m2 comprised 10 cases. The mean RH operating time was 128.1 min (SD 25.3) and the median length of hospital stay was 2 days (range 1–14 days). Increased BMI was associated with small, but statistically significant, increases in operating time and anaesthetic time, 65 additional seconds and 37 seconds, respectively, for each unit increase in BMI. The median self-reported time for individuals who underwent RH to return to their pre-operative activity levels was 4 weeks (range 2 to >12 weeks). There was a significant improvement in pain and physical independence scores over time (p = 0.001 and p < 0.001, respectively) and no significant difference in scores for overall QOL, pain, or physical independence scores was found between the BMI groups. Patient-reported recovery and quality of life following RH is high in individuals with high BMI (over 35 kg/m2) and does not appear to be impacted by the severity of obesity.
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2023
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2023
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2023
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2023
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2022
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2022
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2022
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2021
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2021
Collaborators (3)
Charlotte Edwardson
Associate Professor in Physical Activity, Sedentary Behaviour and Health
University of Leicester
Massimiliano Zecca
Professor of Healthcare Technology
Loughborough University
Luciano Ost
Loughborough University
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