Evan Abt

Adjunct Assistant Professor

UCLA

United States

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Evan Abt is an Adjunct Assistant Professor at UCLA in the United States. His research primarily focuses on nucleoside metabolism, immune responses, and the interplay between cancer and metabolism, as highlighted in his recent publications. Notable articles include studies on mRNA vaccines, small cell neuroendocrine cancer progression, and methodologies for mitigating abscess formation in bacterial infections.

Articles (10)

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2025

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

Collaborators (3)

Volker Winstel

Justus Liebig University Giessen

GERMANY

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Shili Xu

Assistant Professor, Director of Crump Preclinical Imaging Technology Center

UCLA

UNITED STATES

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Willy Hugo

Assistant Professor

David Geffen School of Medicine at UCLA

UNITED STATES

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Evan Abt

Research Interests

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Articles (10)

Landscape of targets within nucleoside metabolism for the modification of immune responses.

Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire

PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity.

Targeting host deoxycytidine kinase mitigates <i>Staphylococcus aureus</i> abscess formation.

<sup>18</sup>F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models

MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell–intrinsic Amplification of Type I IFN Signaling

Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity

Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity.

Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.

Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair

Collaborators (3)

Volker Winstel

Shili Xu

Willy Hugo

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