Evangelos Triantafyllou

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Lecturer in Liver Immunology

Imperial College London

United Kingdom

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About

Evangelos Triantafyllou is a Lecturer in Liver Immunology at Imperial College London, UK. His research primarily focuses on the roles of myeloid cells in liver inflammation and the immune-mediated mechanisms underlying liver injuries. Recent articles highlight his work on macrophage activation markers, checkpoint inhibitors, and the dynamics of gut barrier integrity in relation to liver disease.

Recent Grants

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Checkpoint Inhibitors to Restore Monocyte/Macrophage Function in Liver Failure

Open Date: 2022-03-31

Close Date: 2024-06-29

Articles (20)

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Collaborators (6)

Arjuna Singanayagam

Senior Lecturer in Hepatology

St George’s, University of London

UNITED KINGDOM

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Matthew Siggins

Imperial College London

UNITED KINGDOM

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Francesco Dazzi

King’s College London

UNITED KINGDOM

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Panteleimon Takis

Assistant Professor

University of Ioannina

GREECE

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Chris J. Weston

University of Birmingham

UNITED KINGDOM

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Yan Liu

Senior Lecturer in Glycosciences

Imperial College London

UNITED KINGDOM

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Evangelos Triantafyllou

Research Interests

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About

Recent Grants

Articles (20)

Myeloid cells in chronic liver inflammation

Immune-mediated liver injury from checkpoint inhibitors: mechanisms, clinical characteristics and management

Cis-interaction between CD52 and T cell receptor complex interferes with CD4+ T cell activation in acute decompensation of cirrhosis

Macrophage activation markers are associated with infection and mortality in patients with acute liver failure

Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis

Disruption of gut barrier integrity and host-microbiome interactions underlie MASLD severity in patients with type-2 diabetes mellitus

PTEN loss shapes macrophage dynamics in high grade serous ovarian carcinoma

Peritoneal Immunity in Liver Disease

Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure

AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells

Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure

Potential therapies for acute-on-chronic liver failure

AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells

TAM Receptors in the Pathophysiology of Liver Disease

Lipids in Liver Failure Syndromes: A Focus on Eicosanoids, Specialized Pro-Resolving Lipid Mediators and Lysophospholipids

Suppressor CD4+ T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis

Macrophages in Chronic Liver Failure: Diversity, Plasticity and Therapeutic Targeting

PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury

Activation and transcriptional profile of monocytes and CD8+ T cells are altered in checkpoint inhibitor-related hepatitis

Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis

Collaborators (6)

Arjuna Singanayagam

Matthew Siggins

Francesco Dazzi

Panteleimon Takis

Chris J. Weston

Yan Liu

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