Ewan Smith

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Professor of Nociception

University of Cambridge

United Kingdom

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Professor Ewan Smith is a renowned academic in the field of Nociception at the University of Cambridge, UK. His research encompasses various areas including the mechanisms of pain sensation, the role of inflammatory mediators, and the evolutionary adaptations of sensory systems in subterranean mammals. Recent publications highlight his work on RNA expression, sensory neuron function, and advancements in understanding gastrointestinal biology.

Recent Grants

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In situ production of analgesic peptides for the treatment of joint pain

Open Date: 2022-08-31

Close Date: 2024-08-30

Grant: Close

MICA ADVANTAGE visceral pain consortium: Advanced Discovery of Visceral Analgesics via Neuroimmune Targets and the Genetics of Extreme human phenotype

Open Date: 2021-06-30

Close Date: 2025-06-29

Grant: Close

Non canonical cytokine signalling of haematopoietic growth factors in nociceptor

Open Date: 2020-09-30

Close Date: 2024-09-29

Grant: Close

Targeting the NaV1.7 Interactome for Pain Relief in Arthritis

Open Date: 2018-10-01

Close Date: 2021-09-30

Grant: Close

Functional Characterisation of Putative Mechanoreceptive Neurones in the Colorectum

Open Date: 2018-03-07

Close Date: 2021-03-06

Articles (16)

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2020

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2020

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2020

Collaborators (8)

Walid Khaled

University lecturer

University of Cambridge

UNITED KINGDOM

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Thomas Park

Professor

University of Chicago

UNITED STATES

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Diego Villar

Non-clinical Lecturer

Queen Mary University of London - Whitechapel Campus

UNITED KINGDOM

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Matthew Mason

Professor of Comparative Physiology

University of Cambridge

UNITED KINGDOM

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Laura Peachey

Academic , Associate Professor of Parasitology

University of Bristol

UNITED KINGDOM

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Simon Baeckens

University of Antwerp

BELGIUM

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Van Lu

Assistant Professor

Western University

CANADA

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Gerard Callejo

Lecturer

University of Barcelona

SPAIN

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Ewan Smith

Research Interests

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Contact this professor

About

Recent Grants

Articles (16)

Cap-independent co-expression of dsRNA-sensing and NF-κB pathway inhibitors enables controllable self-amplifying RNA expression with reduced immunotoxicity

Pro-inflammatory mediators sensitise transient receptor potential melastatin 3 cation channel (TRPM3) function in mouse sensory neurons

A note on estimating absolute cytosolic Ca2+ concentration in sensory neurons using a single wavelength Ca2+ indicator

Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory joint pain

Intestinal barrier function in the naked mole-rat: an emergent model for gastrointestinal insights

Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits

Sensitization of colonic nociceptors by IL-13 is dependent on JAK and p38 MAPK activity

Dysregulation of ADAM10 shedding activity in naked mole‐rat fibroblasts is due to deficient phosphatidylserine externalization

Role of Human Mesenchymal Stem Cells and Derived Extracellular Vesicles in Reducing Sensory Neuron Hyperexcitability and Pain Behaviors in Murine Osteoarthritis

Parallel evolution of semicircular canal form and sensitivity in subterranean mammals

Somatic mutation rates scale with lifespan across mammals

Functional Characterization of Ovine Dorsal Root Ganglion Neurons Reveal Peripheral Sensitization after Osteochondral Defect

Acid-sensing ion channel 3: An analgesic target

Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel K<inf>V</inf>6.4 Subunit

Intraarticular Adeno-Associated Virus Serotype AAV-PHP.S–Mediated Chemogenetic Targeting of Knee-Innervating Dorsal Root Ganglion Neurons Alleviates Inflammatory Pain in Mice

Transformation of naked mole-rat cells

Collaborators (8)

Walid Khaled

Thomas Park

Diego Villar

Matthew Mason

Laura Peachey

Simon Baeckens

Van Lu

Gerard Callejo

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