Fanxiu Zhu

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Florida State University

United States

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About

Fanxiu Zhu is a Professor at Florida State University in the United States. His research focuses on the molecular mechanisms of viral replication and immune evasion, particularly concerning Kaposi Sarcoma-Associated Herpesvirus (KSHV). Recent articles authored by him explore topics such as the structural basis of KSHV inhibitor functions, inflammasome activation, and the role of SUMOylation in viral replication.

Recent Grants

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Role of KSHV ORF45 in Viral Immune Evasion &Replication

Open Date: 2005-01-15

Close Date: 2016-03-31

Articles (7)

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2022

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2022

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2022

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2021

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2021

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2021

Year:

2021

Collaborators (1)

Qian Yin

Assistant Professor

Florida State University

UNITED STATES

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Fanxiu Zhu

Research Interests

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About

Recent Grants

Articles (7)

Structural basis of higher order oligomerization of KSHV inhibitor of cGAS

KSHV-encoded ORF45 activates human NLRP1 inflammasome

The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication

RSK1 SUMOylation is required for KSHV lytic replication

Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS

Disruption of the Interaction between ORF33 and the Conserved Carboxyl-Terminus of ORF45 Abolishes Progeny Virion Production of Kaposi Sarcoma-Associated Herpesvirus

Evasion of Intracellular DNA Sensing by Human Herpesviruses

Collaborators (1)

Qian Yin

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