Federica Briani

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Associate professor

Università degli Studi di Torino

Italy

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About

Federica Briani is an Associate Professor at the Università degli Studi di Milano, Italy. Her research focuses on bacteriophages, including viral genome delivery mechanisms and structural analysis of Pseudomonas phages. She has contributed to the understanding of Pseudomonas aeruginosa virulence and the efficacy of phage therapy, using innovative models such as zebrafish.

Recent Grants

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APPROFONDIRE L'ATTIVITÀ ANTIBATTERICA DEI BATTERIOFAGI IN FIBROSI CISTICA PER COMPRENDERE I MECCANISMI ANTINFIAMMATORI E DI ATTIVAZIONE DEL SISTEMA IMMUNITARIO

Open Date: 2022-09-01

Close Date: 2024-08-01

Grant: Close

Tackling phage resistance to increase the robustness of phage therapy for curing Pseudomonas aeruginosa infections in patients with Cystic fibrosis (PhaCyf)

Open Date: 2021-09-01

Close Date: 2022-08-01

Grant: Close

Molecular characterization of disease-linked polynucleotide phosphorylase variants (POLYVAR)

Open Date: 2021-05-01

Close Date: 2024-04-01

Grant: Close

New concepts in the discovery of antibacterial agents: Pseudomonas aeruginosa glucose uptake pathway as a novel drug target

Open Date: 2020-05-01

Close Date: 2021-11-01

Grant: Close

Exploring the role of the glucose uptake pathway in the virulence of Pseudomonas aeruginosa

Open Date: 2017-01-01

Close Date: 2018-03-01

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2020

Collaborators (5)

David Horner

Università degli Studi di Torino

ITALY

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Fenglin Li

University of Pennsylvania

UNITED STATES

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Moira Paroni

Associate Professor in Microbiology

University of Milan

ITALY

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Gino Cingolani

The University of Alabama

UNITED STATES

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PAOLO LANDINI

Professor of General Microbiology

Università degli Studi di Torino

ITALY

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Federica Briani

Research Interests

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About

Recent Grants

Articles (17)

Studying Bacteriophage Efficacy Using a Zebrafish Model.

Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor

Integrative structural analysis of <i>Pseudomonas</i> phage <i>DEV</i> reveals a genome ejection motor

Viral Genome Delivery Across Bacterial Cell Surfaces

Viral Genome Delivery Across Bacterial Cell Surfaces

High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217

Identification and impact on Pseudomonas aeruginosa virulence of mutations conferring resistance to a phage cocktail for phage therapy

High-resolution cryo-EM structure of the <i>Pseudomonas</i> bacteriophage E217

Human PNPase causes RNA stabilization and accumulation of R-loops in the <i>Escherichia coli</i> model system

Identification and impact on <i>Pseudomonas aeruginosa</i> virulence of mutations conferring resistance to a phage cocktail for phage therapy

Evaluation of phages and liposomes as combination therapy to counteract Pseudomonas aeruginosa infection in wild-type and CFTR-null models

Terminase Subunits from the Pseudomonas-Phage E217.

Activity and Function in Human Cells of the Evolutionary Conserved Exonuclease Polynucleotide Phosphorylase

Phages as immunomodulators and their promising use as anti-inflammatory agents in a cftr loss-of-function zebrafish model

Different csrA Expression Levels in C versus K-12 E. coli Strains Affect Biofilm Formation and Impact the Regulatory Mechanism Presided by the CsrB and CsrC Small RNAs

Overexpression of lpxT Gene in Escherichia coli Inhibits Cell Division and Causes Envelope Defects without Changing the Overall Phosphorylation Level of Lipid A

Phage Therapy Application to Counteract <em>Pseudomonas aeruginosa</em> Infection in Cystic Fibrosis Zebrafish Embryos

Collaborators (5)

David Horner

Fenglin Li

Moira Paroni

Gino Cingolani

PAOLO LANDINI

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