Felipe Beckedorff

Research Assistant Professor

University of Miami School of Medicine

United States

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Dr. Felipe Beckedorff is a Research Assistant Professor at the University of Miami School of Medicine, USA. His research focuses on pluripotency maintenance during development, transcriptome mapping, hematopoiesis, DNA:RNA interactions, and the effects of RNA export on cellular sensitivity. He has contributed to understanding the regulatory roles of the Integrator complex and its influence on microRNA abundance and metabolic processes in various cell types.

Articles (17)

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2025

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2021

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2021

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2020

Collaborators (8)

Mirella Meyer-Ficca

Associate Professor

Utah State University

UNITED STATES

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Carolina Magdalen Greco

Assistant Professor

Humanitas University

ITALY

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Skye Montoya

Yale University

UNITED STATES

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Keir J Menzies

Associate Professor

University of Ottawa

CANADA

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Yuki Aoi

Northwestern University Feinberg School of Medicine

UNITED STATES

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Kevin (Kyung) Park

Professor

University of Miami Miller School of Medicine

UNITED STATES

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Shruti Bhatt

Assistant Professor

SINGAPORE

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Ramin Shiekhattar

University of Miami Miller School of Medicine

UNITED STATES

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Felipe Beckedorff

Research Interests

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Articles (17)

Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development

Enhancing transcriptome mapping with rapid PRO-seq profiling of nascent RNA

TAF1 is required for fetal but not adult hematopoiesis in mice

Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition.

Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks

Ecto-CD38-NADase inhibition modulates cardiac metabolism and protects mice against doxorubicin-induced cardiotoxicity

The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression

The Integrator complex regulates microRNA abundance through RISC loading.

Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly

Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide)

Retinal ganglion cell expression of cytokine enhances occupancy of NG2 cell-derived astrocytes at the nerve injury site: Implication for axon regeneration

Identification of long noncoding RNAs in injury-resilient and injury-susceptible mouse retinal ganglion cells

PVT1 signals an androgen-dependent transcriptional repression program in prostate cancer cells and a set of the repressed genes predicts high-risk tumors

Dietary palmitic acid promotes a prometastatic memory via Schwann cells

Integrator enforces the fidelity of transcriptional termination at protein-coding genes

Protein Kinase D–Dependent Downregulation of Immediate Early Genes through Class IIA Histone Deacetylases in Acute Lymphoblastic Leukemia

Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1

Collaborators (8)

Mirella Meyer-Ficca

Carolina Magdalen Greco

Skye Montoya

Keir J Menzies

Yuki Aoi

Kevin (Kyung) Park

Shruti Bhatt

Ramin Shiekhattar

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