Felix Deschner

Helmholtz Institute for Pharmaceutical Research Saarland

Germany

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Articles (8)

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2022

Collaborators (7)

Noran Abdel Wadood

Saarland University

GERMANY

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Susanne Sievers

University of Greifswald

GERMANY

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Jana Held

Eberhard Karls Universität Tübingen

GERMANY

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Laís Pessanha de Carvalho

University of Tübingen

GERMANY

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Ulrich Nübel

Leibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures

GERMANY

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Rolf Müller

GERMANY

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Biao Yuan

University Medical Center Hamburg-Eppendorf

GERMANY

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Felix Deschner

Research Interests

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Articles (8)

Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets

Funktionalisierung von Chlorotonilen: Dehalogenil als vielversprechende Leitverbindung für die in vivo‐Anwendung

Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application

Nitroxoline resistance is associated with significant fitness loss and diminishes in vivo virulence of Escherichia coli

YgiV promoter mutations cause resistance to cystobactamids and reduced virulence factor expression in Escherichia coli

The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection.

Darobactins Exhibiting Superior Antibiotic Activity by Cryo‐EM Structure Guided Biosynthetic Engineering**

Regio‐ and Stereoselective Epoxidation and Acidic Epoxide Opening of Antibacterial and Antiplasmodial Chlorotonils Yield Highly Potent Derivatives

Collaborators (7)

Noran Abdel Wadood

Susanne Sievers

Jana Held

Laís Pessanha de Carvalho

Ulrich Nübel

Rolf Müller

Biao Yuan

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