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Filippo Birocchi

Harvard University

United States

Research Interests

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Articles (16)

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2026

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Collaborators (7)

Robert Manguso

Associate Professor

Harvard Medical School

UNITED STATES

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Chiara Brombin

Assistant Professor in Statistics SECS-S/01 (RTD-B)

Università Vita Salute San Raffaele

ITALY

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Charlotte Graham

King’s College London

UNITED KINGDOM

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Bernhard Gentner

Médecin adjoint (Deputy)

Lausanne University Hospital

SWITZERLAND

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Sangwoo Park

Harvard University

UNITED STATES

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Daniel DeAngelo

Chief of the Division of Leukemia

Dana-Farber Cancer Institute

UNITED STATES

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Stefano Beretta

San Raffaele Telethon Institute for Gene Therapy

ITALY

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Filippo Birocchi

Research Interests

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Articles (16)

Ruxolitinib for Ciltacabtagene Autoleucel-Associated Refractory Diarrhea.

Sialylated CD43 forms a glyco-immune barrier that restrains anti-leukemic immunity

Gene regulatory elements determine efficacy of BCMA-targeted CAR-T cell products

Ibrutinib and PD-1 Blockade Potentiate Mesothelin-Targeting CAR T-cell Therapy in Preclinical Models of Pancreatic Cancer

Rational Engineering of Notch1 Signaling to Boost the Proliferation of CD19-BBζ CAR-T

Genomic correlates of clinical CAR T cell activity

A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice

IFN-γ-resistant CD28 CAR T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models.

CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual-targeting antibody overcome antigen heterogeneity in AML.

Tuning CAR-T cells by targeting cancer-associated glycan in pancreatic cancer

CAR-T cell therapy targeting MUC17 in gastric tumors

Tandem CAR-T cells targeting mesothelin and MUC16 overcome tumor heterogeneity by targeting one antigen at a time

Secretion of a VEGF-Blocking scFv Enhances CAR T-cell Potency

Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma

Chemotherapy-induced reversal of ciltacabtagene autoleucel–associated movement and neurocognitive toxicity

Gene-based delivery of immune-activating cytokines for cancer treatment

Collaborators (7)

Robert Manguso

Chiara Brombin

Charlotte Graham

Bernhard Gentner

Sangwoo Park

Daniel DeAngelo

Stefano Beretta

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