Filippo Prischi

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Senior Lecturer

King’s College London

United Kingdom

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About

Filippo Prischi is a Senior Lecturer at King's College London, UK. His research focuses on molecular interactions and drug design, with recent publications that explore topics such as the identification of small molecule binders, antibiotic resistance mechanisms, and structural studies of protein complexes. He has contributed to the understanding of autophagic processes and therapy resistance in cancer, emphasizing the role of molecular machinery in biological systems.

Recent Grants

Grant: Close

TRICSS - a multi-user high-throughput platform to quantify biological interactions in solution

Open Date: 2023-08-01

Close Date: 2024-07-01

Grant: Close

Flipping the switch; regulating protein synthesis in response to stress

Open Date: 2018-04-01

Close Date:

Grant: Close

Understanding how RSKs regulate Transcription Factors in Triple Negative Breast Cancer

Open Date: 2017-09-04

Close Date: 2019-09-03

Articles (14)

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (7)

Miriam Molina Arcas

The Francis Crick Institute

UNITED KINGDOM

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Federico Galvagni

Prof.

University of Siena

ITALY

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Vassiliy Bavro

Professor of Structural Microbiology

UNITED KINGDOM

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Justin Abi Assaf

University of East Anglia

UNITED KINGDOM

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Mark A. Webber

UNITED KINGDOM

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Greg Brooke

Honorary Lecturer in Oncology

Imperial College London

UNITED KINGDOM

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Ranieri Rossi

University of Siena

ITALY

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Filippo Prischi

Research Interests

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About

Recent Grants

Articles (14)

Enhanced identification of small molecules binding to hnRNPA1 via cryptic pockets mapping coupled with X-ray fragment screening

DrugSynthMC: An Atom-Based Generation of Drug-like Molecules with Monte Carlo Search

Functionally distinct mutations within AcrB underpin antibiotic resistance in different lifestyles

Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches.

Editorial: Weak interactions in molecular machinery volume II.

Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells.

Homogentisic acid induces autophagy alterations leading to chondroptosis in human chondrocytes: Implications in Alkaptonuria.

The role of the p90 ribosomal S6 kinase family in prostate cancer progression and therapy resistance

Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.

Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer

Editorial: Structural Studies of Protein Complexes in Signaling Pathways.

The Role of Ribosomal Protein S6 Kinases in Plant Homeostasis.

Supervised molecular dynamics for exploring the druggability of the SARS-CoV-2 spike protein.

Structural and functional modelling of SARS-CoV-2 entry in animal models.

Collaborators (7)

Miriam Molina Arcas

Federico Galvagni

Vassiliy Bavro

Justin Abi Assaf

Mark A. Webber

Greg Brooke

Ranieri Rossi

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