Flemming Steen Jørgensen

Professor

University of Copenhagen

Denmark

Research Interests

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About

Flemming Steen Jørgensen is a Professor at the University of Copenhagen, Denmark. His research focuses on steroidogenesis, cytochrome P450 enzymes, and the potential therapeutic applications of non-steroidal compounds in prostate cancer. Recent publications include investigations into essential oil components affecting steroidogenic enzymes and novel inhibitors of CYP17A1. Jørgensen’s work combines advanced analytical techniques with molecular studies to explore the mechanisms of drug resistance and receptor interactions.

Articles (10)

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2020

Collaborators (22)

Philip Mark Lund

Technical University of Denmark

DENMARK

Flemming Steen Jørgensen

Research Interests

Contact this professor

About

Articles (10)

Effect of Essential Oil Components on the Activity of Steroidogenic Cytochrome P450

Polypharmacology-labeled molecular networking

Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis

Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment

Differences between the GluD1 and GluD2 receptors revealed by GluD1 X‐ray crystallography, binding studies and molecular dynamics

Synthesis and Structure&ndash;Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents

Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer

Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase

Is the unique benzodiazepine structure interacting with CYP enzymes to affect steroid synthesis in vitro?

Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents.

Collaborators (22)

Philip Mark Lund

Sonia Coriani

Cecilie Cetti Hansen

Tuula Kallunki

Luciano de Oliveira Souza

Yong Zhao

Rahul Yadav

Kenneth Kongstad

Simone Brixius-Anderko

Fredrik Björkling

Dan Staerk

Louise Kjærulff

Saara Kaisa Laulumaa

Henrietta Venter

Sara Thodberg

Jose Moreira

Amit V. Pandey

Tomasz Wróbel

Tomas Laursen

Rita Del Giudice

Kasper Langebjerg Andersen

Birger Lindberg Møller

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Synthesis and Structure–Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents