Florian Hladik

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Research Professor

University of Washington

United States

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About

Florian Hladik is a Research Professor at the University of Washington, USA. His research areas include the immune responses in the female reproductive tract, HIV reservoirs, and the interactions between the microbiome and vaginal health. His recent publications emphasize advancements in studying innate immune mediators, T cell functions, and the implications of host gene expression on viral infections.

Recent Grants

Grant: Close

Extracellular vesicles in semen and genital HIV infection and immunity during heroin addiction and methadone or buprenorphine substitution therapy

Open Date: 2015-07-01

Close Date: 2020-05-31

Grant: Close

Systems and carcinogenic impact assessment of topical microbicides on human mucosa

Open Date: 2015-05-01

Close Date: 2020-04-30

Grant: Close

The Role of Exosomes in Semen for HIV Infection in the Genital Mucosa of Women

Open Date: 2011-03-04

Close Date: 2015-02-28

Grant: Close

Mechanisms of HIV-1 Transmission in the Genital Mucosa of Women

Open Date: 2006-09-29

Close Date: 2010-08-31

Grant: Close

Mechanisms of Sexual HIV-1 Transmission

Open Date: 2002-09-01

Close Date: 2007-05-31

Articles (18)

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2021

Collaborators (8)

Deanna Kroetz

Dean and Professor

Ohio State University

UNITED STATES

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Martin Prlic

Fred Hutchinson Cancer Research Center

UNITED STATES

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Lucia Vojtech

Fred Hutchinson Cancer Research Center

UNITED STATES

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Keith Jerome

Fred Hutchinson Cancer Research Center

UNITED STATES

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Timothy Bell

University of North Carolina

UNITED STATES

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Sean Hughes

University of Washington

UNITED STATES

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Elizabeth Wonderlich

University of Pittsburgh

UNITED STATES

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German Gustavo Gornalusse

Research Assistant Professor

University of Washington

UNITED STATES

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Florian Hladik

Research Interests

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About

Recent Grants

Articles (18)

Effects of Ellagic Acid on Vaginal Innate Immune Mediators and HPV16 Infection In Vitro

Advances and challenges in studying the tissue‐resident T cell compartment in the human female reproductive tract

Memory T cells possess an innate-like function in local protection from mucosal infection

Advances and challenges in studying the tissue-resident T cell compartment in the human female reproductive tract

A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size

Host variation in type I interferon signaling genes (<i>MX1</i>), C-C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV plus noncontrollers predict viral reservoir size

Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen

Upregulation of IFN-stimulated genes persists beyond the transitory broad immunologic changes of acute HIV-1 infection

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling

A review of ex vivo placental perfusion models: an underutilized but promising method to study maternal-fetal interactions

Microbicide Containing Ellagic Acid Can Inhibit HIV-1 Infection

Buprenorphine Increases HIV-1 Infection In Vitro but Does Not Reactivate HIV-1 from Latency

Corrigendum: Potent Restriction of Sexual Zika Virus Infection by the Lipid Fraction of Extracellular Vesicles in Semen (Front. Microbiol., (2020), 11, (574054), 10.3389/fmicb.2020.574054)

The human memory T cell compartment changes across tissues of the female reproductive tract.

HIV reservoir quantification by five-target multiplex droplet digital PCR

Prevalent HPV infection increases the risk of HIV acquisition in African women: advancing the argument for HPV immunization.

A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir.

Impact of the menstrual cycle and ethinyl estradiol/etonogestrel contraceptive vaginal ring on granulysin and other mucosal immune mediators.

Collaborators (8)

Deanna Kroetz

Martin Prlic

Lucia Vojtech

Keith Jerome

Timothy Bell

Sean Hughes

Elizabeth Wonderlich

German Gustavo Gornalusse

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