Florina Moldovan
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About
Florina Moldovan is a professeur at Université de Montréal in Canada. Her research focuses on the design and synthesis of bioactive compounds, with recent contributions exploring modified Vemurafenib analogs and the therapeutic potential of natural sources like Thymus atlanticus. She also investigates animal models for meniscal repair and the regulation of POC5 in various cellular contexts, contributing to the understanding of age-related diseases and osteoarthritis.
Recent Grants
Grant: Close
Functional role of gene variants in adolescent idiopathic scoliosis
Open Date: 2017-04-01
Close Date: 2019-04-01
Articles (7)
Year:
2025
Year:
2024
Thymus atlanticus (Lamiaceae) is a plant endemic to the Mediterranean basin that is found in significant quantities in the arid regions of Morocco. Thymus atlanticus is used in traditional medicine to treat infectious and non-infectious diseases. It is also used for the isolation of essential oils and for the seasoning of many dishes in the Mediterranean diet. The major constituents of Thymus atlanticus are saponins, flavonoids, tannins, alkaloids, various simple and hydroxycinnamic phenolic compounds, and terpene compounds. Several of these compounds act on signaling pathways of oxidative stress, inflammation, and blood sugar, which are parameters often dysregulated during aging. Due to its physiochemical characteristics and biological activities, Thymus atlanticus could be used for the prevention and/or treatment of age-related diseases. These different aspects are treated in the present review, and we focused on phytochemistry and major age-related diseases: dyslipidemia, cardiovascular diseases, and type 2 diabetes.
Year:
2023
Year:
2023
Year:
2022
Year:
2022
Year:
2021
Collaborators (5)
V Gaelle ROULLIN
Associate Professor
Université de Montréal
Gérard Lizard
-
Lélia Bertoni
Senior Lecturer
École nationale vétérinaire d'Alfort
Anne VEJUX
Université de Bourgogne UFR Sciences Vie Terre et Environnement
André Tremblay
Université de Montréal
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