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Flávia Castro

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Junior Researcher

Instituto de Investigação e Inovação em Saúde da Universidade do Porto

Portugal

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Professors in Portugal Professors in Immunology Immunology professors in Portugal

Recent Grants

Grant: Close

HI-DEFENSE : Engineering HybrID Extracellular vesicles For brEast caNcer vacCinE

Open Date: 2026-02-01

Close Date:

Grant: Open

E-MAGIC : ExosoMes-derived rAdioresistance siGnature In breast Cancer

Open Date: 2025-01-01

Close Date: 2028-01-01

Grant: Open

FOCUS- 4R : Fostering Outermost regions Capabilities in Research and Innovation and Upgrading Skills complying with 4R principles

Open Date: 2025-01-01

Close Date: 2028-01-01

Grant: Close

RESOLVE: Rational Design of Multivalent Glycocode-Inspired Nanovaccines for Gastric Cancer Immunotherapy

Open Date: 2022-01-01

Close Date: 2024-01-01

Grant: Close

RADIORESISTANCE - Dissect the tumor microenvironment to battle cancer radioresistance and immune escape

Open Date: 2022-01-01

Close Date:

Articles (19)

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2026

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Andreia Sofia Barros

Junior Researcher

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

PORTUGAL

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Raquel Goncalves

Affiliated Professor

Instituto de Ciências Biomédicas Abel Salazar

PORTUGAL

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Margareta Correia

Senior SCIENTIST

Instituto Português de Oncologia do Porto

PORTUGAL

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Karine Serre

Group Leader

Instituto Gulbenkian de Ciência

PORTUGAL

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Flávia Castro

Research Interests

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Recent Grants

Articles (19)

Targeted nanoparticle delivery of irinotecan enhances tumor response to PD-L1 blockade in colorectal cancer

Systemic administration of poly(I:C) and resiquimod reprograms tumor-associated macrophages and prevents tumor progression and metastasis in murine cancer models

Radiotherapy induces layer-specific molecular and ultrastructural alterations in triple-negative breast cancer spheroids

Novel rectal cancer spheroid models reveal metabolic and transcriptional adaptations driving radiotherapy response

Chitosan/γ-PGA nanoparticles and IFN-γ immunotherapy: A dual approach for triple-negative breast cancer treatment

Emerging mechanisms of triple-negative breast cancer radioresistance: Interplay between cancer cell mechanisms and the tumor immune microenvironment

Protocol to develop a 3D mouse autologous lung tumor-immune spheroid co-culture model to advance radiotherapy-based treatments

Patient-Derived Colorectal Cancer Extracellular Matrices Modulate Cancer Cell Stemness Markers

Engineered dendritic cells-derived extracellular vesicles for cancer immunotherapy

The link between obesity and the gut microbiota and immune system in early-life

Advancing osteosarcoma 3D modeling in vitro for novel tumor microenvironment-targeted therapies development

Targeted and Self-Adjuvated Nanoglycovaccine Candidate for Cancer Immunotherapy

Abstract 715: Nanomedicines loaded with TLR agonists and inhibitors of immunosuppression to reprogram the tumor microenvironment

A multivalent CD44 glycoconjugate vaccine candidate for cancer immunotherapy.

scFv biofunctionalized nanoparticles to effective and safe targeting of CEA-expressing colorectal cancer cells

Mimicking 3D breast tumor-stromal interactions to screen novel cancer therapeutics

Bioprinting Biomimetic 3D Constructs for Tissue Modelling and Repair

Reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of breast cancer

Special Issue: Nanotherapeutics in Women's Health Emerging Nanotechnologies for Triple-Negative Breast Cancer Treatment

Collaborators (9)

Catarina Leite Pereira

Kerry Chester

Joana Paredes

Benedita Sampaio-Maia

Maria João Azevedo

Andreia Sofia Barros

Raquel Goncalves

Margareta Correia

Karine Serre

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