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Franco Falcone

Professor in Parasitology

Justus Liebig Universitat Giessen

Germany

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Research Interests

Pharmaceutical Chemistry

30%

Immunology

40%

Molecular Docking

30%

Chemical Biology

30%

Ligand Design

30%

Immunoassay

20%

Metabolic Engineering

10%

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Articles16

Galactomannan and Vicilin from Fenugreek Seeds (Trigonella foenum-graecum) Impair Early Pathogen-Host Interaction of Campylobacter jejuni with Intestinal Cells via JlpA.

Article Link

Year:

2025

Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors

Article Link

Year:

2024

Front Cover: Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors (ChemMedChem 9/2024)

Article Link

Year:

2024

Inverse Correlation of Th2-Specific Cytokines with Hepatic Egg Burden in S. mansoni-Infected Hamsters

Article Link

Year:

2024

Identification of potent schistosomicidal compounds predicted as type II-kinase inhibitors against Schistosoma mansoni c-Jun N-terminal kinase SMJNK.

Article Link

Year:

2024

Multifunctional interaction of CihC/FbpC orthologs of relapsing fever spirochetes with host-derived proteins involved in adhesion, fibrinolysis, and complement evasion.

Article Link

Year:

2024

Multiplex Immunofluorescence: A Powerful Tool in Cancer Immunotherapy

Article Link

Year:

2023

Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram.

Article Link

Year:

2023

Metabolic reprogramming of hepatocytes by Schistosoma mansoni eggs.

Article Link

Year:

2022

The Humanised NPY-mRFP RBL Reporter Cell Line Is a Fast and Inexpensive Tool for Detection of Allergen-Specific IgE in Human Sera

Article Link

Year:

2022

CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage

Article Link

Year:

2022

Docking-Based Virtual Screening Enables Prioritizing Protein Kinase Inhibitors With In Vitro Phenotypic Activity Against Schistosoma mansoni.

Article Link

Year:

2022

Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis

Article Link

Year:

2022

Introduction of a Hexalysine (6 K) Tag Can Protect from N-Terminal Cleavage and Increase Yield of Recombinant Proteins Expressed in the Periplasm of E. coli.

Article Link

Year:

2022

Are humanized IgE reporter systems potential game changers in serological diagnosis of human parasitic infection?

Article Link

Year:

2021

Does Schistosoma Mansoni Facilitate Carcinogenesis?

Article Link

Year:

2021

Collaborators7

Ahmad Fawzi Hussain

Head of Molecular Gynecology

Justus Liebig University

GERMANY

Eva Böttcher-Friebertshäuser

Philipps-Universität Marburg

GERMANY

Stefanie Gerbig

GERMANY

Jaap J. van Hellemond

Associate professor in parasitology

Erasmus MC

NETHERLANDS

Elke Roeb

Justus Liebig University

GERMANY

Bernhard Spengler

Justus Liebig University

GERMANY

Christoph Grevelding

Full Professor

Justus-Liebig-Universität Giessen Fachbereich Veterinärmedizin

GERMANY

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Franco Falcone

Professor in Parasitology

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Research Interests

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Articles16

Galactomannan and Vicilin from Fenugreek Seeds (Trigonella foenum-graecum) Impair Early Pathogen-Host Interaction of Campylobacter jejuni with Intestinal Cells via JlpA.

Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors

Front Cover: Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors (ChemMedChem 9/2024)

Inverse Correlation of Th2-Specific Cytokines with Hepatic Egg Burden in <i>S. mansoni</i>-Infected Hamsters

Identification of potent schistosomicidal compounds predicted as type II-kinase inhibitors against <i>Schistosoma mansoni</i> c-Jun N-terminal kinase SMJNK.

Multifunctional interaction of CihC/FbpC orthologs of relapsing fever spirochetes with host-derived proteins involved in adhesion, fibrinolysis, and complement evasion.

Multiplex Immunofluorescence: A Powerful Tool in Cancer Immunotherapy

Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram.

Metabolic reprogramming of hepatocytes by <i>Schistosoma mansoni</i> eggs.

The Humanised NPY-mRFP RBL Reporter Cell Line Is a Fast and Inexpensive Tool for Detection of Allergen-Specific IgE in Human Sera

CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage

Docking-Based Virtual Screening Enables Prioritizing Protein Kinase Inhibitors With <i>In Vitro</i> Phenotypic Activity Against Schistosoma mansoni.

Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis

Introduction of a Hexalysine (6 K) Tag Can Protect from N-Terminal Cleavage and Increase Yield of Recombinant Proteins Expressed in the Periplasm of E. coli.

Are humanized IgE reporter systems potential game changers in serological diagnosis of human parasitic infection?

Does Schistosoma Mansoni Facilitate Carcinogenesis?

Collaborators7

Ahmad Fawzi Hussain

Eva Böttcher-Friebertshäuser

Stefanie Gerbig

Jaap J. van Hellemond

Elke Roeb

Bernhard Spengler

Christoph Grevelding

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