Frank Kirchhoff

University professor

Saarland University

Germany

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Frank Kirchhoff is a university professor at the University of Saarland, Germany. His research focuses on neurobiology, particularly the roles of oligodendrocyte precursor cells in neuronal plasticity and demyelination. Recent articles include investigations into autophagy, serotonergic signaling, and therapeutic models for myelin repair, highlighting his contributions to understanding glial cell function in the central nervous system.

Articles (16)

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2025

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2023

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2023

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2023

Collaborators (9)

Wenhui Huang

Saarland University

GERMANY

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Peter Göttle

Heinrich Heine University Düsseldorf

GERMANY

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Christian Henneberger

GERMANY

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Xianshu Bai

GERMANY

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Michael Wegner

Professor

Friedrich-Alexander Universität Erlangen-Nürnberg

GERMANY

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Melanie Küspert

Friedrich-Alexander Universität Erlangen-Nürnberg

GERMANY

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Feng Han

Deutsches Krebsforschungszentrum

GERMANY

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Julio Esparza

SPAIN

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Jean-Yves Tinevez

Core Facility Head

Institut Pasteur

FRANCE

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Frank Kirchhoff

Research Interests

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Articles (16)

Impaired Macroautophagy in Oligodendrocyte Precursor Cells Suppresses Neuronal Plasticity via a Senescence Associated Signaling

Oligodendrocyte precursor cells facilitate neuronal lysosome release.

Genetic Downregulation of GABA<sub>B</sub> Receptors from Oligodendrocyte Precursor Cells Protects Against Demyelination in the Mouse Spinal Cord

Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex

Effects of local and systemic treatment with human natural killer-1 mimetic peptide (HNK-1) after ventral root avulsion and reimplantation in mice

Differential activity of transcription factor Sox9 in early and adult oligodendroglial progenitor cells

In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury

A Novel Ex Vivo Model to Study Therapeutic Treatments for Myelin Repair following Ischemic Damage

Dysfunction of NG2 glial cells affects neuronal plasticity and behavior

LPS-Induced Systemic Inflammation Affects the Dynamic Interactions of Astrocytes and Microglia with the Vasculature of the Mouse Brain Cortex

Analysis of a cell niche with proliferative potential at the roof of the aqueduct of Sylvius

Specific detection and deletion of the sigma‐1 receptor widely expressed in neurons and glial cells in vivo

Activating NO–sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury

A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning

Contribution of Intravital Neuroimaging to Study Animal Models of Multiple Sclerosis

Dysfunctional serotonergic neuron-astrocyte signaling in depressive-like states

Collaborators (9)

Wenhui Huang

Peter Göttle

Christian Henneberger

Xianshu Bai

Michael Wegner

Melanie Küspert

Feng Han

Julio Esparza

Jean-Yves Tinevez

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